Insulin and glucose metabolism with olanzapine and a combination of olanzapine and samidorphan: exploratory phase 1 results in healthy volunteers

A combination of olanzapine and samidorphan (OLZ/SAM) received US Food and Drug Administration approval in May 2021 for the treatment of adults with schizophrenia or bipolar I disorder. OLZ/SAM provides the efficacy of olanzapine, while mitigating olanzapine-associated weight gain. This exploratory...

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Detalles Bibliográficos
Autores principales: Toledo, Frederico G. S., Martin, William F., Morrow, Linda, Beysen, Carine, Bajorunas, Daiva, Jiang, Ying, Silverman, Bernard L., McDonnell, David, Namchuk, Mark N., Newcomer, John W., Graham, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8782841/
https://www.ncbi.nlm.nih.gov/pubmed/34887529
http://dx.doi.org/10.1038/s41386-021-01244-7

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