RICH1 inhibits breast cancer stem cell traits through activating kinases cascade of Hippo signaling by competing with Merlin for binding to Amot-p80

Cancer stem cells (CSCs) are regarded as the root of tumor recurrence and distant metastasis, as well as the major cause of resistance to conventional cancer therapies. Elucidating the mechanism of regulating CSCs is of great significance for the development of CSCs-targeting therapy strategies. YAP...

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Detalles Bibliográficos
Autores principales: Tian, Qi, Gao, Huan, Zhou, Yan, Zhu, Lizhe, Yang, Jiao, Wang, Bo, Liu, Peijun, Yang, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8782888/
https://www.ncbi.nlm.nih.gov/pubmed/35064101
http://dx.doi.org/10.1038/s41419-022-04516-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8782888/
https://www.ncbi.nlm.nih.gov/pubmed/35064101
http://dx.doi.org/10.1038/s41419-022-04516-2

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