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RNA binding protein NKAP protects glioblastoma cells from ferroptosis by promoting SLC7A11 mRNA splicing in an m(6)A-dependent manner

Ferroptosis is a form of cell death characterized by lipid peroxidation. Previous studies have reported that knockout of NF-κB activating protein (NKAP), an RNA-binding protein, increased lipid peroxidation level in naive T cells and induced cell death in colon cancer cells. However, there was no li...

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Detalles Bibliográficos
Autores principales: Sun, Shicheng, Gao, Taihong, Pang, Bo, Su, Xiangsheng, Guo, Changfa, Zhang, Rui, Pang, Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8783023/
https://www.ncbi.nlm.nih.gov/pubmed/35064112
http://dx.doi.org/10.1038/s41419-022-04524-2