Oncolytic vaccinia virus injected intravenously sensitizes pancreatic neuroendocrine tumors and metastases to immune checkpoint blockade

This study determined the influence of intravenous (i.v.) oncolytic vaccinia virus mpJX-594 (mpJX) on antitumor activity of anti-programmed death receptor-1 antibody (aPD1) in functional and metastatic pancreatic neuroendocrine tumors (PanNETs). One i.v. dose of mpJX, engineered for mice with the sa...

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Detalles Bibliográficos
Autores principales: Inoue, Mitsuko, Kim, Minah, Inoue, Tomoyoshi, Tait, Madeline, Byrne, Thomas, Nitschké, Maximilian, Murer, Patrizia, Cha, Howard, Subramanian, Aishwarya, De Silva, Naomi, Chiaverotti, Teresa, McDonald, Donald M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8783073/
https://www.ncbi.nlm.nih.gov/pubmed/35118189
http://dx.doi.org/10.1016/j.omto.2021.12.016

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