Self-assembled tetrahedral framework nucleic acid mediates tumor-associated macrophage reprogramming and restores antitumor immunity

There is increasing interest in depleting or repolarizing tumor-associated macrophages (TAMs) to generate a proinflammatory effect. However, TAMs usually display an immunosuppressive M2-like phenotype in the tumor microenvironment. Apparently, developing a macrophage-targeting delivery system with i...

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Detalles Bibliográficos
Autores principales: Qian, Husun, Zhou, Ting, Fu, Yixin, Guo, Minkang, Yang, Wu, Zhang, Dian, Fang, Wenli, Yao, Mengli, Shi, He, Chai, Chengsen, Cheng, Wei, Ding, Shijia, Chen, Tingmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8783116/
https://www.ncbi.nlm.nih.gov/pubmed/35116188
http://dx.doi.org/10.1016/j.omtn.2021.12.036

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