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Current progress in neuroimaging research for the treatment of major depression with electroconvulsive therapy

Electroconvulsive therapy (ECT) uses a certain amount of electric current to pass through the head of the patient, causing convulsions throughout the body, to relieve the symptoms of the disease and achieve the purpose of treatment. ECT can effectively improve the clinical symptoms of patients with...

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Detalles Bibliográficos
Autores principales: Li, Xin-Ke, Qiu, Hai-Tang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8783162/
https://www.ncbi.nlm.nih.gov/pubmed/35111584
http://dx.doi.org/10.5498/wjp.v12.i1.128
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author Li, Xin-Ke
Qiu, Hai-Tang
author_facet Li, Xin-Ke
Qiu, Hai-Tang
author_sort Li, Xin-Ke
collection PubMed
description Electroconvulsive therapy (ECT) uses a certain amount of electric current to pass through the head of the patient, causing convulsions throughout the body, to relieve the symptoms of the disease and achieve the purpose of treatment. ECT can effectively improve the clinical symptoms of patients with major depression, but its therapeutic mechanism is still unclear. With the rapid development of neuroimaging technology, it is necessary to explore the neurobiological mechanism of major depression from the aspects of brain structure, brain function and brain metabolism, and to find that ECT can improve the brain function, metabolism and even brain structure of patients to a certain extent. Currently, an increasing number of neuroimaging studies adopt various neuroimaging techniques including functional magnetic resonance imaging (MRI), positron emission tomography, magnetic resonance spectroscopy, structural MRI, and diffusion tensor imaging to reveal the neural effects of ECT. This article reviews the recent progress in neuroimaging research on ECT for major depression. The results suggest that the neurobiological mechanism of ECT may be to modulate the functional activity and connectivity or neural structural plasticity in specific brain regions to the normal level, to achieve the therapeutic effect.
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spelling pubmed-87831622022-02-01 Current progress in neuroimaging research for the treatment of major depression with electroconvulsive therapy Li, Xin-Ke Qiu, Hai-Tang World J Psychiatry Minireviews Electroconvulsive therapy (ECT) uses a certain amount of electric current to pass through the head of the patient, causing convulsions throughout the body, to relieve the symptoms of the disease and achieve the purpose of treatment. ECT can effectively improve the clinical symptoms of patients with major depression, but its therapeutic mechanism is still unclear. With the rapid development of neuroimaging technology, it is necessary to explore the neurobiological mechanism of major depression from the aspects of brain structure, brain function and brain metabolism, and to find that ECT can improve the brain function, metabolism and even brain structure of patients to a certain extent. Currently, an increasing number of neuroimaging studies adopt various neuroimaging techniques including functional magnetic resonance imaging (MRI), positron emission tomography, magnetic resonance spectroscopy, structural MRI, and diffusion tensor imaging to reveal the neural effects of ECT. This article reviews the recent progress in neuroimaging research on ECT for major depression. The results suggest that the neurobiological mechanism of ECT may be to modulate the functional activity and connectivity or neural structural plasticity in specific brain regions to the normal level, to achieve the therapeutic effect. Baishideng Publishing Group Inc 2022-01-19 /pmc/articles/PMC8783162/ /pubmed/35111584 http://dx.doi.org/10.5498/wjp.v12.i1.128 Text en ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. https://creativecommons.org/licenses/by-nc/4.0/This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
spellingShingle Minireviews
Li, Xin-Ke
Qiu, Hai-Tang
Current progress in neuroimaging research for the treatment of major depression with electroconvulsive therapy
title Current progress in neuroimaging research for the treatment of major depression with electroconvulsive therapy
title_full Current progress in neuroimaging research for the treatment of major depression with electroconvulsive therapy
title_fullStr Current progress in neuroimaging research for the treatment of major depression with electroconvulsive therapy
title_full_unstemmed Current progress in neuroimaging research for the treatment of major depression with electroconvulsive therapy
title_short Current progress in neuroimaging research for the treatment of major depression with electroconvulsive therapy
title_sort current progress in neuroimaging research for the treatment of major depression with electroconvulsive therapy
topic Minireviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8783162/
https://www.ncbi.nlm.nih.gov/pubmed/35111584
http://dx.doi.org/10.5498/wjp.v12.i1.128
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