Cargando…
A Smartphone App to Improve Oral Anticoagulation Adherence in Patients With Atrial Fibrillation: Prospective Observational Study
BACKGROUND: Poor adherence to oral anticoagulation in elderly patients with atrial fibrillation (AF) has been shown to negatively impact health care costs, morbidity, and mortality. Although various methods such as automated reminders, counseling, telephone support, and patient education have been e...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
JMIR Publications
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8783280/ https://www.ncbi.nlm.nih.gov/pubmed/34894626 http://dx.doi.org/10.2196/30807 |
_version_ | 1784638503300104192 |
---|---|
author | Senoo, Keitaro Miki, Tomonori Ohkura, Takashi Iwakoshi, Hibiki Nishimura, Tetsuro Shiraishi, Hirokazu Teramukai, Satoshi Matoba, Satoaki |
author_facet | Senoo, Keitaro Miki, Tomonori Ohkura, Takashi Iwakoshi, Hibiki Nishimura, Tetsuro Shiraishi, Hirokazu Teramukai, Satoshi Matoba, Satoaki |
author_sort | Senoo, Keitaro |
collection | PubMed |
description | BACKGROUND: Poor adherence to oral anticoagulation in elderly patients with atrial fibrillation (AF) has been shown to negatively impact health care costs, morbidity, and mortality. Although various methods such as automated reminders, counseling, telephone support, and patient education have been effective in improving medication adherence, the burden on health care providers has been considerable. Recently, an attempt has been made to improve medication adherence without burdening health care providers by using smartphone apps; however, the use of the app for elderly patients with AF is still limited. OBJECTIVE: The purpose of this study was to determine whether the newly developed smartphone app for patients with AF (the Smart AF), which integrates education, automatic reminder, and patient engagement strategies with a simple user interface, can improve medication adherence in elderly patients with AF. METHODS: Patient enrollment was carried out by obtaining informed consent from patients with AF attending Kyoto Prefectural University of Medicine hospital between May 2019 and September 2020. Follow-up was planned at 1, 3, and 6 months after enrollment, and questionnaire reminders were automatically sent to patient apps at designated follow-up time points. A questionnaire-based survey of medication adherence was performed electronically using the self-reported 8-item Morisky Medication Adherence Scale (MMAS-8) as the survey tool. RESULTS: A total of 136 patients with AF were enrolled in this study. During the follow-up period, 112 (82%) patients underwent follow-up at 1 month, 107 (79%) at 3 months, and 96 (71%) at 6 months. The mean age of the enrolled patients was 64.3 years (SD 9.6), and male participants accounted for 79.4% (108/136) of the study population. The mean CHADS2 (congestive heart failure, hypertension, age, diabetes, previous stroke, or transient ischemic attack) score was 1.2, with hypertension being the most common comorbidity. At the time of enrollment, 126 (93%) and 10 (7%) patients were taking direct oral anticoagulants and warfarin, respectively. For medication adherence as measured according to the MMAS-8, MMAS scores at 1 month, 3 months, and 6 months were significantly improved compared with baseline MMAS scores (all P values less than .01). The overall improvement in medication adherence achieved by the 6-month intervention was as follows: 77.8% (14/18) of the patients in the high adherence group (score=8) at baseline remained in the same state, 45.3% (24/53) of the patients in the medium adherence group (score=6 to <8) at baseline moved to the high adherence group, and 72% (18/25) of the patients in the low adherence group (score <6) moved to either the medium or high adherence group. CONCLUSIONS: The Smart AF app improved medication adherence among elderly patients with AF. In the realm of medication management, an approach using a mobile health technology that emphasizes education, automatic reminder, and patient engagement may be helpful. |
format | Online Article Text |
id | pubmed-8783280 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | JMIR Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-87832802022-02-03 A Smartphone App to Improve Oral Anticoagulation Adherence in Patients With Atrial Fibrillation: Prospective Observational Study Senoo, Keitaro Miki, Tomonori Ohkura, Takashi Iwakoshi, Hibiki Nishimura, Tetsuro Shiraishi, Hirokazu Teramukai, Satoshi Matoba, Satoaki JMIR Mhealth Uhealth Original Paper BACKGROUND: Poor adherence to oral anticoagulation in elderly patients with atrial fibrillation (AF) has been shown to negatively impact health care costs, morbidity, and mortality. Although various methods such as automated reminders, counseling, telephone support, and patient education have been effective in improving medication adherence, the burden on health care providers has been considerable. Recently, an attempt has been made to improve medication adherence without burdening health care providers by using smartphone apps; however, the use of the app for elderly patients with AF is still limited. OBJECTIVE: The purpose of this study was to determine whether the newly developed smartphone app for patients with AF (the Smart AF), which integrates education, automatic reminder, and patient engagement strategies with a simple user interface, can improve medication adherence in elderly patients with AF. METHODS: Patient enrollment was carried out by obtaining informed consent from patients with AF attending Kyoto Prefectural University of Medicine hospital between May 2019 and September 2020. Follow-up was planned at 1, 3, and 6 months after enrollment, and questionnaire reminders were automatically sent to patient apps at designated follow-up time points. A questionnaire-based survey of medication adherence was performed electronically using the self-reported 8-item Morisky Medication Adherence Scale (MMAS-8) as the survey tool. RESULTS: A total of 136 patients with AF were enrolled in this study. During the follow-up period, 112 (82%) patients underwent follow-up at 1 month, 107 (79%) at 3 months, and 96 (71%) at 6 months. The mean age of the enrolled patients was 64.3 years (SD 9.6), and male participants accounted for 79.4% (108/136) of the study population. The mean CHADS2 (congestive heart failure, hypertension, age, diabetes, previous stroke, or transient ischemic attack) score was 1.2, with hypertension being the most common comorbidity. At the time of enrollment, 126 (93%) and 10 (7%) patients were taking direct oral anticoagulants and warfarin, respectively. For medication adherence as measured according to the MMAS-8, MMAS scores at 1 month, 3 months, and 6 months were significantly improved compared with baseline MMAS scores (all P values less than .01). The overall improvement in medication adherence achieved by the 6-month intervention was as follows: 77.8% (14/18) of the patients in the high adherence group (score=8) at baseline remained in the same state, 45.3% (24/53) of the patients in the medium adherence group (score=6 to <8) at baseline moved to the high adherence group, and 72% (18/25) of the patients in the low adherence group (score <6) moved to either the medium or high adherence group. CONCLUSIONS: The Smart AF app improved medication adherence among elderly patients with AF. In the realm of medication management, an approach using a mobile health technology that emphasizes education, automatic reminder, and patient engagement may be helpful. JMIR Publications 2022-01-07 /pmc/articles/PMC8783280/ /pubmed/34894626 http://dx.doi.org/10.2196/30807 Text en ©Keitaro Senoo, Tomonori Miki, Takashi Ohkura, Hibiki Iwakoshi, Tetsuro Nishimura, Hirokazu Shiraishi, Satoshi Teramukai, Satoaki Matoba. Originally published in JMIR mHealth and uHealth (https://mhealth.jmir.org), 07.01.2022. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in JMIR mHealth and uHealth, is properly cited. The complete bibliographic information, a link to the original publication on https://mhealth.jmir.org/, as well as this copyright and license information must be included. |
spellingShingle | Original Paper Senoo, Keitaro Miki, Tomonori Ohkura, Takashi Iwakoshi, Hibiki Nishimura, Tetsuro Shiraishi, Hirokazu Teramukai, Satoshi Matoba, Satoaki A Smartphone App to Improve Oral Anticoagulation Adherence in Patients With Atrial Fibrillation: Prospective Observational Study |
title | A Smartphone App to Improve Oral Anticoagulation Adherence in Patients With Atrial Fibrillation: Prospective Observational Study |
title_full | A Smartphone App to Improve Oral Anticoagulation Adherence in Patients With Atrial Fibrillation: Prospective Observational Study |
title_fullStr | A Smartphone App to Improve Oral Anticoagulation Adherence in Patients With Atrial Fibrillation: Prospective Observational Study |
title_full_unstemmed | A Smartphone App to Improve Oral Anticoagulation Adherence in Patients With Atrial Fibrillation: Prospective Observational Study |
title_short | A Smartphone App to Improve Oral Anticoagulation Adherence in Patients With Atrial Fibrillation: Prospective Observational Study |
title_sort | smartphone app to improve oral anticoagulation adherence in patients with atrial fibrillation: prospective observational study |
topic | Original Paper |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8783280/ https://www.ncbi.nlm.nih.gov/pubmed/34894626 http://dx.doi.org/10.2196/30807 |
work_keys_str_mv | AT senookeitaro asmartphoneapptoimproveoralanticoagulationadherenceinpatientswithatrialfibrillationprospectiveobservationalstudy AT mikitomonori asmartphoneapptoimproveoralanticoagulationadherenceinpatientswithatrialfibrillationprospectiveobservationalstudy AT ohkuratakashi asmartphoneapptoimproveoralanticoagulationadherenceinpatientswithatrialfibrillationprospectiveobservationalstudy AT iwakoshihibiki asmartphoneapptoimproveoralanticoagulationadherenceinpatientswithatrialfibrillationprospectiveobservationalstudy AT nishimuratetsuro asmartphoneapptoimproveoralanticoagulationadherenceinpatientswithatrialfibrillationprospectiveobservationalstudy AT shiraishihirokazu asmartphoneapptoimproveoralanticoagulationadherenceinpatientswithatrialfibrillationprospectiveobservationalstudy AT teramukaisatoshi asmartphoneapptoimproveoralanticoagulationadherenceinpatientswithatrialfibrillationprospectiveobservationalstudy AT matobasatoaki asmartphoneapptoimproveoralanticoagulationadherenceinpatientswithatrialfibrillationprospectiveobservationalstudy AT senookeitaro smartphoneapptoimproveoralanticoagulationadherenceinpatientswithatrialfibrillationprospectiveobservationalstudy AT mikitomonori smartphoneapptoimproveoralanticoagulationadherenceinpatientswithatrialfibrillationprospectiveobservationalstudy AT ohkuratakashi smartphoneapptoimproveoralanticoagulationadherenceinpatientswithatrialfibrillationprospectiveobservationalstudy AT iwakoshihibiki smartphoneapptoimproveoralanticoagulationadherenceinpatientswithatrialfibrillationprospectiveobservationalstudy AT nishimuratetsuro smartphoneapptoimproveoralanticoagulationadherenceinpatientswithatrialfibrillationprospectiveobservationalstudy AT shiraishihirokazu smartphoneapptoimproveoralanticoagulationadherenceinpatientswithatrialfibrillationprospectiveobservationalstudy AT teramukaisatoshi smartphoneapptoimproveoralanticoagulationadherenceinpatientswithatrialfibrillationprospectiveobservationalstudy AT matobasatoaki smartphoneapptoimproveoralanticoagulationadherenceinpatientswithatrialfibrillationprospectiveobservationalstudy |