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Giant dorsal lipofibromatosis in an infant: a case report

BACKGROUND: Lipofibromatosis is a rare, benign, soft tissue tumor that usually presents in children. Low incidence and lack of specificity in clinical presentation make its diagnosis difficult. CASE PRESENTATION: This is a case report of a patient with a giant lipofibromatosis on the back that resem...

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Autores principales: Li, Zhiyu, Zou, Yuqing, Xu, Guangqi, Bi, Jianhai, Huo, Ran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8783458/
https://www.ncbi.nlm.nih.gov/pubmed/35065637
http://dx.doi.org/10.1186/s12887-022-03130-7
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author Li, Zhiyu
Zou, Yuqing
Xu, Guangqi
Bi, Jianhai
Huo, Ran
author_facet Li, Zhiyu
Zou, Yuqing
Xu, Guangqi
Bi, Jianhai
Huo, Ran
author_sort Li, Zhiyu
collection PubMed
description BACKGROUND: Lipofibromatosis is a rare, benign, soft tissue tumor that usually presents in children. Low incidence and lack of specificity in clinical presentation make its diagnosis difficult. CASE PRESENTATION: This is a case report of a patient with a giant lipofibromatosis on the back that resembles an infantile hemangioma, which posed great difficulty in diagnosis due to atypical clinical manifestations. After the postoperative pathological and immunohistochemical examination and fluorescence in situ hybridization, the patient was finally diagnosed with lipofibromatosis. CONCLUSIONS: The incidence of fibromatosis was low. This case presents an atypical clinical manifestation since the tumor growth was on the back, and this can easily cause misdiagnosis. This case suggests that the diagnosis of lipofibromatosis depends on the pathology and fluorescence in situ hybridization.
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spelling pubmed-87834582022-01-24 Giant dorsal lipofibromatosis in an infant: a case report Li, Zhiyu Zou, Yuqing Xu, Guangqi Bi, Jianhai Huo, Ran BMC Pediatr Case Report BACKGROUND: Lipofibromatosis is a rare, benign, soft tissue tumor that usually presents in children. Low incidence and lack of specificity in clinical presentation make its diagnosis difficult. CASE PRESENTATION: This is a case report of a patient with a giant lipofibromatosis on the back that resembles an infantile hemangioma, which posed great difficulty in diagnosis due to atypical clinical manifestations. After the postoperative pathological and immunohistochemical examination and fluorescence in situ hybridization, the patient was finally diagnosed with lipofibromatosis. CONCLUSIONS: The incidence of fibromatosis was low. This case presents an atypical clinical manifestation since the tumor growth was on the back, and this can easily cause misdiagnosis. This case suggests that the diagnosis of lipofibromatosis depends on the pathology and fluorescence in situ hybridization. BioMed Central 2022-01-22 /pmc/articles/PMC8783458/ /pubmed/35065637 http://dx.doi.org/10.1186/s12887-022-03130-7 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Case Report
Li, Zhiyu
Zou, Yuqing
Xu, Guangqi
Bi, Jianhai
Huo, Ran
Giant dorsal lipofibromatosis in an infant: a case report
title Giant dorsal lipofibromatosis in an infant: a case report
title_full Giant dorsal lipofibromatosis in an infant: a case report
title_fullStr Giant dorsal lipofibromatosis in an infant: a case report
title_full_unstemmed Giant dorsal lipofibromatosis in an infant: a case report
title_short Giant dorsal lipofibromatosis in an infant: a case report
title_sort giant dorsal lipofibromatosis in an infant: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8783458/
https://www.ncbi.nlm.nih.gov/pubmed/35065637
http://dx.doi.org/10.1186/s12887-022-03130-7
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AT bijianhai giantdorsallipofibromatosisinaninfantacasereport
AT huoran giantdorsallipofibromatosisinaninfantacasereport