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Prokaryotic expression, purification and evaluation of anti-cardiac fibrosis activity of recombinant TGF-β latency associated peptide

BACKGROUND: Cardiac fibrosis refers to the abnormal accumulation of extracellular matrix in the heart, which leads to the formation of cardiac scars. It causes systolic and diastolic dysfunction, and ultimately leads to cardiac dysfunction and arrhythmia. TGF-β1 is an important regulatory factor inv...

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Detalles Bibliográficos
Autores principales: Song, Xudong, Qiu, Yufei, Shi, Jiayi, Li, Luxin, Yuan, Xiaohuan, Wu, Dan, Chu, Yanhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8783559/
https://www.ncbi.nlm.nih.gov/pubmed/35111409
http://dx.doi.org/10.7717/peerj.12797