In Silico Exploration of Novel Tubulin Inhibitors: A Combination of Docking and Molecular Dynamics Simulations, Pharmacophore Modeling, and Virtual Screening

Microtubules play a critical role in mitosis and cell division and are regarded as an excellent target for anticancer therapy. Although microtubule-targeting agents have been widely used in the clinical treatment of different human cancers, their clinical application in cancer therapy is limited by...

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Detalles Bibliográficos
Autores principales: Hadizadeh, Farzin, Ghodsi, Razieh, Mirzaei, Salimeh, Sahebkar, Amirhossein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8783753/
https://www.ncbi.nlm.nih.gov/pubmed/35075369
http://dx.doi.org/10.1155/2022/4004068

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8783753/
https://www.ncbi.nlm.nih.gov/pubmed/35075369
http://dx.doi.org/10.1155/2022/4004068

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