Intestinal commensal microbiota and cytokines regulate Fut2(+) Paneth cells for gut defense

Paneth cells are intestinal epithelial cells that release antimicrobial peptides, such as α-defensin as part of host defense. Together with mesenchymal cells, Paneth cells provide niche factors for epithelial stem cell homeostasis. Here, we report two subtypes of murine Paneth cells, differentiated...

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Detalles Bibliográficos
Autores principales: Kamioka, Mariko, Goto, Yoshiyuki, Nakamura, Kiminori, Yokoi, Yuki, Sugimoto, Rina, Ohira, Shuya, Kurashima, Yosuke, Umemoto, Shingo, Sato, Shintaro, Kunisawa, Jun, Takahashi, Yu, Domino, Steven E., Renauld, Jean-Christophe, Nakae, Susumu, Iwakura, Yoichiro, Ernst, Peter B., Ayabe, Tokiyoshi, Kiyono, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8784097/
https://www.ncbi.nlm.nih.gov/pubmed/35027453
http://dx.doi.org/10.1073/pnas.2115230119

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