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Floxed exon (Flexon): A flexibly positioned stop cassette for recombinase-mediated conditional gene expression
Conditional gene expression is a powerful tool for genetic analysis of biological phenomena. In the widely used “lox-stop-lox” approach, insertion of a stop cassette consisting of a series of stop codons and polyadenylation signals flanked by lox sites into the 5′ untranslated region (UTR) of a gene...
Autores principales: | Shaffer, Justin M., Greenwald, Iva |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8784106/ https://www.ncbi.nlm.nih.gov/pubmed/35027456 http://dx.doi.org/10.1073/pnas.2117451119 |
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