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PDGF-D−PDGFRβ signaling enhances IL-15–mediated human natural killer cell survival

The axis of platelet-derived growth factor (PDGF) and PDGF receptor-beta (PDGFRβ) plays prominent roles in cell growth and motility. In addition, PDGF-D enhances human natural killer (NK) cell effector functions when binding to the NKp44 receptor. Here, we report an additional but previously unknown...

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Detalles Bibliográficos
Autores principales: Ma, Shoubao, Tang, Tingting, Wu, Xiaojin, Mansour, Anthony G., Lu, Ting, Zhang, Jianying, Wang, Li-Shu, Caligiuri, Michael A., Yu, Jianhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8784126/
https://www.ncbi.nlm.nih.gov/pubmed/35027451
http://dx.doi.org/10.1073/pnas.2114134119