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GATOR2 complex–mediated amino acid signaling regulates brain myelination
Amino acids are essential for cell growth and metabolism. Amino acid and growth factor signaling pathways coordinately regulate the mechanistic target of rapamycin complex 1 (mTORC1) kinase in cell growth and organ development. While major components of amino acid signaling mechanisms have been iden...
Autores principales: | Yu, Zongyan, Yang, Zhiwen, Ren, Guoru, Wang, Yingjie, Luo, Xiang, Zhu, Feiyan, Yu, Shouyang, Jia, Lanlan, Chen, Mina, Worley, Paul F., Xiao, Bo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8784133/ https://www.ncbi.nlm.nih.gov/pubmed/35022234 http://dx.doi.org/10.1073/pnas.2110917119 |
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