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Association of Lipid and Body Mass Index Profile With Chronic Hepatitis C Infection Stratified by Age and Gender

Background In this study, we aimed to determine the association of lipid and body mass index (BMI) profiles among cases having chronic hepatitis C virus (CHCV) infection. Methodology This cross-sectional study was conducted in the outpatient department of a tertiary care hospital. A total of 320 cas...

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Autores principales: Maqsood, H, Chughtai, Tamoor, Khan, Abdul Basit, Younus, Shifa, Abbas, Akifa, Akbar, Usman A, Qazi, Shaheryar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8784145/
https://www.ncbi.nlm.nih.gov/pubmed/35103215
http://dx.doi.org/10.7759/cureus.20665
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author Maqsood, H
Chughtai, Tamoor
Khan, Abdul Basit
Younus, Shifa
Abbas, Akifa
Akbar, Usman A
Qazi, Shaheryar
author_facet Maqsood, H
Chughtai, Tamoor
Khan, Abdul Basit
Younus, Shifa
Abbas, Akifa
Akbar, Usman A
Qazi, Shaheryar
author_sort Maqsood, H
collection PubMed
description Background In this study, we aimed to determine the association of lipid and body mass index (BMI) profiles among cases having chronic hepatitis C virus (CHCV) infection. Methodology This cross-sectional study was conducted in the outpatient department of a tertiary care hospital. A total of 320 cases of both genders, aged 18 to 60 years, with CHCV infection were enrolled in the study. After obtaining relevant history and conducting a physical examination, the venous blood sample of each patient was taken and sent to the institutional laboratory to analyze serum total cholesterol, serum triglyceride, low-density lipoprotein, and high-density lipoprotein levels. BMI of all the study participants was also noted. Results Of the total 320 cases, there were 152 (47.5%) males and 168 (52.5%) females. The overall mean age was 42.92 ± 11.38 years. Most cases [97 (30.3%)] were in the 41 to 50-year age group. Overall, the mean BMI was 27.75 ± 4.59 kg/m(2). Dyslipidemia was noted in 144 (45.0%) cases. Increasing age and increasing BMI were found to have statistical significance with the presence of dyslipidemia (p < 0.05). Conclusions Increasing age and BMI have a significant association with dyslipidemia in patients with CHCV infection. Lipid profile appears to differ among different age and BMI groups.
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spelling pubmed-87841452022-01-30 Association of Lipid and Body Mass Index Profile With Chronic Hepatitis C Infection Stratified by Age and Gender Maqsood, H Chughtai, Tamoor Khan, Abdul Basit Younus, Shifa Abbas, Akifa Akbar, Usman A Qazi, Shaheryar Cureus Internal Medicine Background In this study, we aimed to determine the association of lipid and body mass index (BMI) profiles among cases having chronic hepatitis C virus (CHCV) infection. Methodology This cross-sectional study was conducted in the outpatient department of a tertiary care hospital. A total of 320 cases of both genders, aged 18 to 60 years, with CHCV infection were enrolled in the study. After obtaining relevant history and conducting a physical examination, the venous blood sample of each patient was taken and sent to the institutional laboratory to analyze serum total cholesterol, serum triglyceride, low-density lipoprotein, and high-density lipoprotein levels. BMI of all the study participants was also noted. Results Of the total 320 cases, there were 152 (47.5%) males and 168 (52.5%) females. The overall mean age was 42.92 ± 11.38 years. Most cases [97 (30.3%)] were in the 41 to 50-year age group. Overall, the mean BMI was 27.75 ± 4.59 kg/m(2). Dyslipidemia was noted in 144 (45.0%) cases. Increasing age and increasing BMI were found to have statistical significance with the presence of dyslipidemia (p < 0.05). Conclusions Increasing age and BMI have a significant association with dyslipidemia in patients with CHCV infection. Lipid profile appears to differ among different age and BMI groups. Cureus 2021-12-24 /pmc/articles/PMC8784145/ /pubmed/35103215 http://dx.doi.org/10.7759/cureus.20665 Text en Copyright © 2021, Maqsood et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Maqsood, H
Chughtai, Tamoor
Khan, Abdul Basit
Younus, Shifa
Abbas, Akifa
Akbar, Usman A
Qazi, Shaheryar
Association of Lipid and Body Mass Index Profile With Chronic Hepatitis C Infection Stratified by Age and Gender
title Association of Lipid and Body Mass Index Profile With Chronic Hepatitis C Infection Stratified by Age and Gender
title_full Association of Lipid and Body Mass Index Profile With Chronic Hepatitis C Infection Stratified by Age and Gender
title_fullStr Association of Lipid and Body Mass Index Profile With Chronic Hepatitis C Infection Stratified by Age and Gender
title_full_unstemmed Association of Lipid and Body Mass Index Profile With Chronic Hepatitis C Infection Stratified by Age and Gender
title_short Association of Lipid and Body Mass Index Profile With Chronic Hepatitis C Infection Stratified by Age and Gender
title_sort association of lipid and body mass index profile with chronic hepatitis c infection stratified by age and gender
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8784145/
https://www.ncbi.nlm.nih.gov/pubmed/35103215
http://dx.doi.org/10.7759/cureus.20665
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