Cargando…

Sporadic and Lynch syndrome-associated mismatch repair-deficient brain tumors

Mismatch repair-deficient (MMRD) brain tumors are rare among primary brain tumors and can be induced by germline or sporadic mutations. Here, we report 13 MMRD-associated (9 sporadic and 4 Lynch syndrome) primary brain tumors to determine clinicopathological and molecular characteristics and biologi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kim, Hyunhee, Lim, Ka Young, Park, Jin Woo, Kang, Jeongwan, Won, Jae Kyung, Lee, Kwanghoon, Shim, Yumi, Park, Chul-Kee, Kim, Seung-Ki, Choi, Seung-Hong, Kim, Tae Min, Yun, Hongseok, Park, Sung-Hye
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group US 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8784316/ https://www.ncbi.nlm.nih.gov/pubmed/34848827 http://dx.doi.org/10.1038/s41374-021-00694-3

Ejemplares similares

Molecular subtyping of ependymoma and prognostic impact of Ki-67
por: Lim, Ka Young, et al.
Publicado: (2021)

Prevalence and Prognosis of Lynch Syndrome and Sporadic Mismatch Repair Deficiency in Endometrial Cancer
por: Post, Cathalijne C B, et al.
Publicado: (2021)

MYB/MYBL1::QKI fusion-positive diffuse glioma
por: Suh, Ye Yoon, et al.
Publicado: (2023)

The prognostic significance of p16 expression pattern in diffuse gliomas
por: Park, Jin Woo, et al.
Publicado: (2021)

Macrophagic myofasciitis and subcutaneous pseudolymphoma caused by aluminium adjuvants
por: Kim, Hyunhee, et al.
Publicado: (2020)

Prevalence of Lynch syndrome in women with mismatch repair‐deficient ovarian cancer
por: Hodan, Rachel, et al.
Publicado: (2020)

Mismatch repair deficiency testing in Lynch syndrome-associated urothelial tumors
por: Rasmussen, Maria, et al.
Publicado: (2023)

Cost-effective screening using a two-antibody panel for detecting mismatch repair deficiency in sporadic colorectal cancer
por: Kim, Jong Beom, et al.
Publicado: (2021)

Genomic profiles of IDH-mutant gliomas: MYCN-amplified IDH-mutant astrocytoma had the worst prognosis
por: Lee, Kwanghoon, et al.
Publicado: (2023)

Challenges of Neoantigen Targeting in Lynch Syndrome and Constitutional Mismatch Repair Deficiency Syndrome
por: Abidi, Asima, et al.
Publicado: (2021)

Comparison of oncologic outcomes between patients with Lynch syndrome and sporadic microsatellite instability-high colorectal cancer
por: Son, Il Tae, et al.
Publicado: (2021)

Is it all Lynch Syndrome? An assessment of family history in individuals with mismatch repair deficient tumors
por: Dempsey, Katherine M., et al.
Publicado: (2014)

Deficient mismatch repair system in patients with sporadic advanced colorectal cancer
por: Koopman, M, et al.
Publicado: (2009)

Correlating programmed death ligand 1 (PD-L1) expression, mismatch repair deficiency, and outcomes across tumor types: implications for immunotherapy
por: Kim, Seung Tae, et al.
Publicado: (2017)

Mismatch Repair-Deficient Crypt Foci in Lynch Syndrome – Molecular Alterations and Association with Clinical Parameters
por: Staffa, Laura, et al.
Publicado: (2015)

Prevalence of mismatch repair deficiency and Lynch syndrome in a cohort of unselected small bowel adenocarcinomas
por: Suerink, Manon, et al.
Publicado: (2021)

Integrating Tumor Sequencing Into Clinical Practice for Patients With Mismatch Repair-Deficient Lynch Syndrome Spectrum Cancers
por: Dixon, Katherine, et al.
Publicado: (2021)

Tumor-independent Detection of Inherited Mismatch Repair Deficiency for the Diagnosis of Lynch Syndrome with High Specificity and Sensitivity
por: Kansikas, Minttu, et al.
Publicado: (2023)

Toxic leukoencephalopathy with axonal spheroids caused by chemotherapeutic drugs other than methotrexate
por: Lim, Ka Young, et al.
Publicado: (2022)

Frequent mismatch-repair defects link prostate cancer to Lynch syndrome
por: Dominguez-Valentin, Mev, et al.
Publicado: (2016)

Distinct Immunological Landscapes Characterize Inherited and Sporadic Mismatch Repair Deficient Endometrial Cancer
por: Ramchander, Neal C., et al.
Publicado: (2020)

Excluding Lynch syndrome in a female patient with metachronous DNA mismatch repair deficient colon- and ovarian cancer
por: Crobach, Stijn, et al.
Publicado: (2017)

Lynch syndrome–associated ultra-hypermutated pediatric glioblastoma mimicking a constitutional mismatch repair deficiency syndrome
por: Yang, Chen, et al.
Publicado: (2019)

Pancreatic cancer ‘mismatch’ in Lynch syndrome
por: Hendifar, Andrew E, et al.
Publicado: (2019)

Streamlining the use of IHC in identifying germline mismatch repair mutations in Lynch syndrome
por: Rea, Gillian, et al.
Publicado: (2012)

Hereditary Aspects of Colorectal Cancer: Mismatch Repair Genes Drive Lynch Syndrome
por: Hampel, Heather, et al.
Publicado: (2018)

Mismatch Repair Screening of Gastrointestinal Cancers: The Impact on Lynch Syndrome Detection and Immunotherapy
por: R., Openshaw M., et al.
Publicado: (2022)

TumorNext-Lynch-MMR: a comprehensive next generation sequencing assay for the detection of germline and somatic mutations in genes associated with mismatch repair deficiency and Lynch syndrome
por: Gray, Phillip N., et al.
Publicado: (2018)

Molecular Basis of Mismatch Repair Protein Deficiency in Tumors from Lynch Suspected Cases with Negative Germline Test Results
por: Olkinuora, Alisa, et al.
Publicado: (2020)

Non-classical phenotypes of mismatch repair deficiency and microsatellite instability in primary and metastatic tumors at different sites in Lynch syndrome
por: Li, Zhiyu, et al.
Publicado: (2022)

A tumor focused approach to resolving the etiology of DNA mismatch repair deficient tumors classified as suspected Lynch syndrome
por: Walker, Romy, et al.
Publicado: (2023)

A tumor focused approach to resolving the etiology of DNA mismatch repair deficient tumors classified as suspected Lynch syndrome
por: Walker, Romy, et al.
Publicado: (2023)

DNA Mismatch Repair Gene Variants in Sporadic Solid Cancers
por: Caja, Fabian, et al.
Publicado: (2020)

Mismatch repair-deficient status associates with favorable prognosis of Eastern Chinese population with sporadic colorectal cancer
por: Gong, Qing, et al.
Publicado: (2018)

Mismatch repair gene mutations lead to lynch syndrome colorectal cancer in rhesus macaques
por: Dray, Beth K., et al.
Publicado: (2018)

Comprehensive mismatch repair gene panel identifies variants in patients with Lynch‐like syndrome
por: Xavier, Alexandre, et al.
Publicado: (2019)

Screening of Lynch syndrome in endometrial cancer in Iranian population with mismatch repair protein by immunohistochemistry
por: Noei Teymoordash, Somayyeh, et al.
Publicado: (2022)

Clinical problems of colorectal cancer and endometrial cancer cases with unknown cause of tumor mismatch repair deficiency (suspected Lynch syndrome)
por: Buchanan, Daniel D, et al.
Publicado: (2014)

Mismatch repair–deficient glioma with spatially distinct IDH-mutant and IDH-wild type components arising in the setting of Lynch syndrome
por: Tan, Hao, et al.
Publicado: (2023)

The prevalence of lynch syndrome (DNA mismatch repair protein deficiency) in patients with primary localized prostate cancer using immunohistochemistry screening
por: Oka, Suguru, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_buerne1kchigo4rjvull9o2gv7