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Myeloid sarcoma of uterine cervix: A case report with review of the literature

Myeloid sarcoma is a rare clinical entity, characterised by the extramedullary presence of myeloblasts. It can occur de novo or signify disease recurrence. Involvement of the female reproductive tract is uncommon, with most cases involving the uterine corpus or ovary. Patients with non-leukaemic mye...

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Detalles Bibliográficos
Autores principales: Mullen, C., Beverstock, S., Roddie, H., Campbell, V.L., Al-Qsous, W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8784329/
https://www.ncbi.nlm.nih.gov/pubmed/35106356
http://dx.doi.org/10.1016/j.gore.2022.100931
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author Mullen, C.
Beverstock, S.
Roddie, H.
Campbell, V.L.
Al-Qsous, W.
author_facet Mullen, C.
Beverstock, S.
Roddie, H.
Campbell, V.L.
Al-Qsous, W.
author_sort Mullen, C.
collection PubMed
description Myeloid sarcoma is a rare clinical entity, characterised by the extramedullary presence of myeloblasts. It can occur de novo or signify disease recurrence. Involvement of the female reproductive tract is uncommon, with most cases involving the uterine corpus or ovary. Patients with non-leukaemic myeloid sarcoma are treated with acute myeloid leukaemia (AML) regimens, but the optimal therapy is unclear due to the relative rarity of the condition and lack of clinical trial data. We present an unusual case of myeloid sarcoma of the uterine cervix diagnosed incidentally in a patient with cervical-intraepithelial neoplasia grade 2 (CIN2), followed by a literature review.
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spelling pubmed-87843292022-01-31 Myeloid sarcoma of uterine cervix: A case report with review of the literature Mullen, C. Beverstock, S. Roddie, H. Campbell, V.L. Al-Qsous, W. Gynecol Oncol Rep Case Reports and Case Series Myeloid sarcoma is a rare clinical entity, characterised by the extramedullary presence of myeloblasts. It can occur de novo or signify disease recurrence. Involvement of the female reproductive tract is uncommon, with most cases involving the uterine corpus or ovary. Patients with non-leukaemic myeloid sarcoma are treated with acute myeloid leukaemia (AML) regimens, but the optimal therapy is unclear due to the relative rarity of the condition and lack of clinical trial data. We present an unusual case of myeloid sarcoma of the uterine cervix diagnosed incidentally in a patient with cervical-intraepithelial neoplasia grade 2 (CIN2), followed by a literature review. Elsevier 2022-01-14 /pmc/articles/PMC8784329/ /pubmed/35106356 http://dx.doi.org/10.1016/j.gore.2022.100931 Text en © 2022 Published by Elsevier Inc. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Reports and Case Series
Mullen, C.
Beverstock, S.
Roddie, H.
Campbell, V.L.
Al-Qsous, W.
Myeloid sarcoma of uterine cervix: A case report with review of the literature
title Myeloid sarcoma of uterine cervix: A case report with review of the literature
title_full Myeloid sarcoma of uterine cervix: A case report with review of the literature
title_fullStr Myeloid sarcoma of uterine cervix: A case report with review of the literature
title_full_unstemmed Myeloid sarcoma of uterine cervix: A case report with review of the literature
title_short Myeloid sarcoma of uterine cervix: A case report with review of the literature
title_sort myeloid sarcoma of uterine cervix: a case report with review of the literature
topic Case Reports and Case Series
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8784329/
https://www.ncbi.nlm.nih.gov/pubmed/35106356
http://dx.doi.org/10.1016/j.gore.2022.100931
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