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Myeloid sarcoma of uterine cervix: A case report with review of the literature
Myeloid sarcoma is a rare clinical entity, characterised by the extramedullary presence of myeloblasts. It can occur de novo or signify disease recurrence. Involvement of the female reproductive tract is uncommon, with most cases involving the uterine corpus or ovary. Patients with non-leukaemic mye...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8784329/ https://www.ncbi.nlm.nih.gov/pubmed/35106356 http://dx.doi.org/10.1016/j.gore.2022.100931 |
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author | Mullen, C. Beverstock, S. Roddie, H. Campbell, V.L. Al-Qsous, W. |
author_facet | Mullen, C. Beverstock, S. Roddie, H. Campbell, V.L. Al-Qsous, W. |
author_sort | Mullen, C. |
collection | PubMed |
description | Myeloid sarcoma is a rare clinical entity, characterised by the extramedullary presence of myeloblasts. It can occur de novo or signify disease recurrence. Involvement of the female reproductive tract is uncommon, with most cases involving the uterine corpus or ovary. Patients with non-leukaemic myeloid sarcoma are treated with acute myeloid leukaemia (AML) regimens, but the optimal therapy is unclear due to the relative rarity of the condition and lack of clinical trial data. We present an unusual case of myeloid sarcoma of the uterine cervix diagnosed incidentally in a patient with cervical-intraepithelial neoplasia grade 2 (CIN2), followed by a literature review. |
format | Online Article Text |
id | pubmed-8784329 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-87843292022-01-31 Myeloid sarcoma of uterine cervix: A case report with review of the literature Mullen, C. Beverstock, S. Roddie, H. Campbell, V.L. Al-Qsous, W. Gynecol Oncol Rep Case Reports and Case Series Myeloid sarcoma is a rare clinical entity, characterised by the extramedullary presence of myeloblasts. It can occur de novo or signify disease recurrence. Involvement of the female reproductive tract is uncommon, with most cases involving the uterine corpus or ovary. Patients with non-leukaemic myeloid sarcoma are treated with acute myeloid leukaemia (AML) regimens, but the optimal therapy is unclear due to the relative rarity of the condition and lack of clinical trial data. We present an unusual case of myeloid sarcoma of the uterine cervix diagnosed incidentally in a patient with cervical-intraepithelial neoplasia grade 2 (CIN2), followed by a literature review. Elsevier 2022-01-14 /pmc/articles/PMC8784329/ /pubmed/35106356 http://dx.doi.org/10.1016/j.gore.2022.100931 Text en © 2022 Published by Elsevier Inc. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Case Reports and Case Series Mullen, C. Beverstock, S. Roddie, H. Campbell, V.L. Al-Qsous, W. Myeloid sarcoma of uterine cervix: A case report with review of the literature |
title | Myeloid sarcoma of uterine cervix: A case report with review of the literature |
title_full | Myeloid sarcoma of uterine cervix: A case report with review of the literature |
title_fullStr | Myeloid sarcoma of uterine cervix: A case report with review of the literature |
title_full_unstemmed | Myeloid sarcoma of uterine cervix: A case report with review of the literature |
title_short | Myeloid sarcoma of uterine cervix: A case report with review of the literature |
title_sort | myeloid sarcoma of uterine cervix: a case report with review of the literature |
topic | Case Reports and Case Series |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8784329/ https://www.ncbi.nlm.nih.gov/pubmed/35106356 http://dx.doi.org/10.1016/j.gore.2022.100931 |
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