Tumor necrosis factor α upregulates the bile acid efflux transporter OATP3A1 via multiple signaling pathways in cholestasis

Cholestasis is a common condition in which the flow of bile from the liver to the intestines is inhibited. It has been shown that organic anion–transporting polypeptide 3A1 (OATP3A1) is upregulated in cholestasis to promote bile acid efflux transport. We have previously shown that the growth factor...

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Detalles Bibliográficos
Autores principales: Li, Mingqiao, Wang, Weihua, Cheng, Ying, Zhang, Xiaoxun, Zhao, Nan, Tan, Ya, Xie, Qiaoling, Chai, Jin, Pan, Qiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8784341/
https://www.ncbi.nlm.nih.gov/pubmed/34971708
http://dx.doi.org/10.1016/j.jbc.2021.101543

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