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Within and Beyond the Nucleotide Addition Cycle of Viral RNA-dependent RNA Polymerases
Nucleotide addition cycle (NAC) is a fundamental process utilized by nucleic acid polymerases when carrying out nucleic acid biosynthesis. An induced-fit mechanism is usually taken by these polymerases upon NTP/dNTP substrate binding, leading to active site closure and formation of a phosphodiester...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8784604/ https://www.ncbi.nlm.nih.gov/pubmed/35083282 http://dx.doi.org/10.3389/fmolb.2021.822218 |