Immunization with synthetic SARS-CoV-2 S glycoprotein virus-like particles protects macaques from infection

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has caused an ongoing global health crisis. Here, we present as a vaccine candidate synthetic SARS-CoV-2 spike (S) glycoprotein-coated lipid vesicles that resemble virus-like particles. Soluble S glycoprotein trimer stabilizat...

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Detalles Bibliográficos
Autores principales: Sulbaran, Guidenn, Maisonnasse, Pauline, Amen, Axelle, Effantin, Gregory, Guilligay, Delphine, Dereuddre-Bosquet, Nathalie, Burger, Judith A., Poniman, Meliawati, Grobben, Marloes, Buisson, Marlyse, Dergan Dylon, Sebastian, Naninck, Thibaut, Lemaître, Julien, Gros, Wesley, Gallouët, Anne-Sophie, Marlin, Romain, Bouillier, Camille, Contreras, Vanessa, Relouzat, Francis, Fenel, Daphna, Thepaut, Michel, Bally, Isabelle, Thielens, Nicole, Fieschi, Franck, Schoehn, Guy, van der Werf, Sylvie, van Gils, Marit J., Sanders, Rogier W., Poignard, Pascal, Le Grand, Roger, Weissenhorn, Winfried
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8784613/
https://www.ncbi.nlm.nih.gov/pubmed/35233549
http://dx.doi.org/10.1016/j.xcrm.2022.100528

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