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Watching liquid droplets of TDP-43(CTD) age by Raman spectroscopy

Liquid–liquid phase separation (LLPS) is a biological phenomenon wherein a metastable and concentrated droplet phase of biomolecules spontaneously forms. A link may exist between LLPS of proteins and the disease-related process of amyloid fibril formation; however, this connection is not fully under...

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Detalles Bibliográficos
Autores principales: Shuster, Sydney O., Lee, Jennifer C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8784639/
https://www.ncbi.nlm.nih.gov/pubmed/34953857
http://dx.doi.org/10.1016/j.jbc.2021.101528