A community challenge for a pancancer drug mechanism of action inference from perturbational profile data

The Columbia Cancer Target Discovery and Development (CTD2) Center is developing PANACEA, a resource comprising dose-responses and RNA sequencing (RNA-seq) profiles of 25 cell lines perturbed with ∼400 clinical oncology drugs, to study a tumor-specific drug mechanism of action. Here, this resource s...

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Detalles Bibliográficos
Autores principales: Douglass, Eugene F., Allaway, Robert J., Szalai, Bence, Wang, Wenyu, Tian, Tingzhong, Fernández-Torras, Adrià, Realubit, Ron, Karan, Charles, Zheng, Shuyu, Pessia, Alberto, Tanoli, Ziaurrehman, Jafari, Mohieddin, Wan, Fangping, Li, Shuya, Xiong, Yuanpeng, Duran-Frigola, Miquel, Bertoni, Martino, Badia-i-Mompel, Pau, Mateo, Lídia, Guitart-Pla, Oriol, Chung, Verena, Tang, Jing, Zeng, Jianyang, Aloy, Patrick, Saez-Rodriguez, Julio, Guinney, Justin, Gerhard, Daniela S., Califano, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8784774/
https://www.ncbi.nlm.nih.gov/pubmed/35106508
http://dx.doi.org/10.1016/j.xcrm.2021.100492

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8784774/
https://www.ncbi.nlm.nih.gov/pubmed/35106508
http://dx.doi.org/10.1016/j.xcrm.2021.100492

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