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Post-traumatic Stress Disorder Symptoms and Quality of Life of COVID-19 Survivors at 6-Month Follow-Up: A Cross-Sectional Observational Study

Background: Post-traumatic stress disorder (PTSD) is the most common psychiatric sequelae among novel coronavirus disease (COVID-19) patients. The aim of this study was to determine the prevalence of PTSD symptoms, PTSD-related factors, and its relationship with quality of life at long-term follow-u...

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Autores principales: Huang, Liqun, Xu, Xiaohua, Zhang, Lingjie, Zheng, Danwen, Liu, Yuntao, Feng, Bing, Hu, Jiajun, Lin, Qiaoli, Xi, Xiaotu, Wang, Qian, Lin, Meixuan, Zhou, Xin, He, Zehui, Weng, Heng, Deng, Qiuying, Ding, Banghan, Guo, Jianwen, Zhang, Zhongde
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8784850/
https://www.ncbi.nlm.nih.gov/pubmed/35082700
http://dx.doi.org/10.3389/fpsyt.2021.782478
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author Huang, Liqun
Xu, Xiaohua
Zhang, Lingjie
Zheng, Danwen
Liu, Yuntao
Feng, Bing
Hu, Jiajun
Lin, Qiaoli
Xi, Xiaotu
Wang, Qian
Lin, Meixuan
Zhou, Xin
He, Zehui
Weng, Heng
Deng, Qiuying
Ding, Banghan
Guo, Jianwen
Zhang, Zhongde
author_facet Huang, Liqun
Xu, Xiaohua
Zhang, Lingjie
Zheng, Danwen
Liu, Yuntao
Feng, Bing
Hu, Jiajun
Lin, Qiaoli
Xi, Xiaotu
Wang, Qian
Lin, Meixuan
Zhou, Xin
He, Zehui
Weng, Heng
Deng, Qiuying
Ding, Banghan
Guo, Jianwen
Zhang, Zhongde
author_sort Huang, Liqun
collection PubMed
description Background: Post-traumatic stress disorder (PTSD) is the most common psychiatric sequelae among novel coronavirus disease (COVID-19) patients. The aim of this study was to determine the prevalence of PTSD symptoms, PTSD-related factors, and its relationship with quality of life at long-term follow-up in hospitalized COVID-19 survivors. Methods: A cross-sectional study was undertaken to evaluate the health consequences of hospitalized COVID-19 survivors. All participants were interviewed face-to-face through a series of questionnaires: a researcher-developed symptom questionnaire, the Post-traumatic Stress Disorder Checklist–Civilian Version, the Generalized Anxiety Disorder 7-item, and the 36-item Short Form. Results: A total of 574 participants were enrolled with an average age of 57 years. The median follow-up time post-discharge was 193.9 days (SD = 15.32). Among the participants, 77.9% of survivors presented with at least one symptom, where fatigue or muscle weakness (47.9%) was reported the most frequently, followed by chest distress (29.4%) and sleep difficulty (29.4%). The prevalence of PTSD was 11.15% [95% confidence interval (CI): 8.56, 13.73] with a cut-off score of 44. Factors such as respiratory symptoms [odds ratio (OR): 3.53; 95% CI: 1.68–7.42], anxiety (OR: 14.64; 95% CI: 7.09–30.21), and sleep difficulty (OR: 2.17; 95% CI: 1.14–4.16) were positively related to PTSD. Those COVID-19 survivors with potential PTSD had significantly lower quality of life than those without (P < 0.05). Conclusion: Our study illustrated that a significant number of COVID-19 survivors were suffering from physical or mental distress to varying degrees at 6 months post-discharge. People with PTSD were more likely to experience persistent respiratory symptoms and sleep difficulty, as well as anxiety and a decreased quality of life. Such survivors require greater attention to their mental health, particularly the PTSD symptoms at the early phase, which may play an important role in the recovery of both the physical and psychological health of COVID-19 survivors.
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spelling pubmed-87848502022-01-25 Post-traumatic Stress Disorder Symptoms and Quality of Life of COVID-19 Survivors at 6-Month Follow-Up: A Cross-Sectional Observational Study Huang, Liqun Xu, Xiaohua Zhang, Lingjie Zheng, Danwen Liu, Yuntao Feng, Bing Hu, Jiajun Lin, Qiaoli Xi, Xiaotu Wang, Qian Lin, Meixuan Zhou, Xin He, Zehui Weng, Heng Deng, Qiuying Ding, Banghan Guo, Jianwen Zhang, Zhongde Front Psychiatry Psychiatry Background: Post-traumatic stress disorder (PTSD) is the most common psychiatric sequelae among novel coronavirus disease (COVID-19) patients. The aim of this study was to determine the prevalence of PTSD symptoms, PTSD-related factors, and its relationship with quality of life at long-term follow-up in hospitalized COVID-19 survivors. Methods: A cross-sectional study was undertaken to evaluate the health consequences of hospitalized COVID-19 survivors. All participants were interviewed face-to-face through a series of questionnaires: a researcher-developed symptom questionnaire, the Post-traumatic Stress Disorder Checklist–Civilian Version, the Generalized Anxiety Disorder 7-item, and the 36-item Short Form. Results: A total of 574 participants were enrolled with an average age of 57 years. The median follow-up time post-discharge was 193.9 days (SD = 15.32). Among the participants, 77.9% of survivors presented with at least one symptom, where fatigue or muscle weakness (47.9%) was reported the most frequently, followed by chest distress (29.4%) and sleep difficulty (29.4%). The prevalence of PTSD was 11.15% [95% confidence interval (CI): 8.56, 13.73] with a cut-off score of 44. Factors such as respiratory symptoms [odds ratio (OR): 3.53; 95% CI: 1.68–7.42], anxiety (OR: 14.64; 95% CI: 7.09–30.21), and sleep difficulty (OR: 2.17; 95% CI: 1.14–4.16) were positively related to PTSD. Those COVID-19 survivors with potential PTSD had significantly lower quality of life than those without (P < 0.05). Conclusion: Our study illustrated that a significant number of COVID-19 survivors were suffering from physical or mental distress to varying degrees at 6 months post-discharge. People with PTSD were more likely to experience persistent respiratory symptoms and sleep difficulty, as well as anxiety and a decreased quality of life. Such survivors require greater attention to their mental health, particularly the PTSD symptoms at the early phase, which may play an important role in the recovery of both the physical and psychological health of COVID-19 survivors. Frontiers Media S.A. 2022-01-10 /pmc/articles/PMC8784850/ /pubmed/35082700 http://dx.doi.org/10.3389/fpsyt.2021.782478 Text en Copyright © 2022 Huang, Xu, Zhang, Zheng, Liu, Feng, Hu, Lin, Xi, Wang, Lin, Zhou, He, Weng, Deng, Ding, Guo and Zhang. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Psychiatry
Huang, Liqun
Xu, Xiaohua
Zhang, Lingjie
Zheng, Danwen
Liu, Yuntao
Feng, Bing
Hu, Jiajun
Lin, Qiaoli
Xi, Xiaotu
Wang, Qian
Lin, Meixuan
Zhou, Xin
He, Zehui
Weng, Heng
Deng, Qiuying
Ding, Banghan
Guo, Jianwen
Zhang, Zhongde
Post-traumatic Stress Disorder Symptoms and Quality of Life of COVID-19 Survivors at 6-Month Follow-Up: A Cross-Sectional Observational Study
title Post-traumatic Stress Disorder Symptoms and Quality of Life of COVID-19 Survivors at 6-Month Follow-Up: A Cross-Sectional Observational Study
title_full Post-traumatic Stress Disorder Symptoms and Quality of Life of COVID-19 Survivors at 6-Month Follow-Up: A Cross-Sectional Observational Study
title_fullStr Post-traumatic Stress Disorder Symptoms and Quality of Life of COVID-19 Survivors at 6-Month Follow-Up: A Cross-Sectional Observational Study
title_full_unstemmed Post-traumatic Stress Disorder Symptoms and Quality of Life of COVID-19 Survivors at 6-Month Follow-Up: A Cross-Sectional Observational Study
title_short Post-traumatic Stress Disorder Symptoms and Quality of Life of COVID-19 Survivors at 6-Month Follow-Up: A Cross-Sectional Observational Study
title_sort post-traumatic stress disorder symptoms and quality of life of covid-19 survivors at 6-month follow-up: a cross-sectional observational study
topic Psychiatry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8784850/
https://www.ncbi.nlm.nih.gov/pubmed/35082700
http://dx.doi.org/10.3389/fpsyt.2021.782478
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