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Statement on the active substance acetamiprid
Acetamiprid is a pesticide active substance with insecticidal action currently under the third renewal (AIR3) of the Commission implementing regulation (EU) No 844/2012. Following concerns that this substance may pose high risks to humans and the environment, the French authorities asked the Commiss...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8784984/ https://www.ncbi.nlm.nih.gov/pubmed/35106090 http://dx.doi.org/10.2903/j.efsa.2022.7031 |
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author | Hernandez Jerez, Antonio Adriaanse, Paulien Berny, Philippe Coja, Tamara Duquesne, Sabine Focks, Andreas Marinovich, Marina Millet, Maurice Pelkonen, Olavi Pieper, Silvia Tiktak, Aaldrik Topping, Christopher Widenfalk, Anneli Wilks, Martin Wolterink, Gerrit Rundlöf, Maj Ippolito, Alessio Linguadoca, Alberto Martino, Laura Panzarea, Martina Terron, Andrea Aldrich, Annette |
author_facet | Hernandez Jerez, Antonio Adriaanse, Paulien Berny, Philippe Coja, Tamara Duquesne, Sabine Focks, Andreas Marinovich, Marina Millet, Maurice Pelkonen, Olavi Pieper, Silvia Tiktak, Aaldrik Topping, Christopher Widenfalk, Anneli Wilks, Martin Wolterink, Gerrit Rundlöf, Maj Ippolito, Alessio Linguadoca, Alberto Martino, Laura Panzarea, Martina Terron, Andrea Aldrich, Annette |
collection | PubMed |
description | Acetamiprid is a pesticide active substance with insecticidal action currently under the third renewal (AIR3) of the Commission implementing regulation (EU) No 844/2012. Following concerns that this substance may pose high risks to humans and the environment, the French authorities asked the Commission to restrict its uses under Article 69 of Regulation (EC) No 1107/2009. To support this request, competent Authorities from France cited a series of literature papers investigating its hazards and/or exposure to humans and the environment. Consequently, the EFSA PPR Panel was mandated to advise on the likelihood that body of evidence would constitute proof of serious risks to humans or the environment. Therefore, the EFSA PPR Panel evaluated the likelihood of these studies indicating new or higher hazards and exposure to humans and the environment compared to previous EU assessments.A stepwise methodology was designed, including: (i) the initial screening; (ii) the data extraction and critical appraisal based on the principles of OHAT/NTP; (iii) the weight of evidence, including consideration of the previous EU assessments; (iv) the uncertainty analysis, followed, whenever relevant, by an expert knowledge elicitation process. For human health, no conclusive evidence of higher hazards compared to previous assessment was found for genotoxicity, developmental toxicity, neurotoxicity including developmental neurotoxicity and immunotoxicity. However, due to the lack of adequate assessment of the current data set, the PPR Panel recommends conducting an assessment of endocrine disrupting properties for acetamiprid in line with EFSA/ECHA guidance document for the identification of endocrine disruptors. For environment, no conclusive, robust evidence of higher hazards compared to the previous assessment was found for birds, aquatic organisms, bees and soil organisms. However, the potential of high inter‐species sensitivity of birds and bees towards acetamiprid requires further consideration. |
format | Online Article Text |
id | pubmed-8784984 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-87849842022-01-31 Statement on the active substance acetamiprid Hernandez Jerez, Antonio Adriaanse, Paulien Berny, Philippe Coja, Tamara Duquesne, Sabine Focks, Andreas Marinovich, Marina Millet, Maurice Pelkonen, Olavi Pieper, Silvia Tiktak, Aaldrik Topping, Christopher Widenfalk, Anneli Wilks, Martin Wolterink, Gerrit Rundlöf, Maj Ippolito, Alessio Linguadoca, Alberto Martino, Laura Panzarea, Martina Terron, Andrea Aldrich, Annette EFSA J Statement Acetamiprid is a pesticide active substance with insecticidal action currently under the third renewal (AIR3) of the Commission implementing regulation (EU) No 844/2012. Following concerns that this substance may pose high risks to humans and the environment, the French authorities asked the Commission to restrict its uses under Article 69 of Regulation (EC) No 1107/2009. To support this request, competent Authorities from France cited a series of literature papers investigating its hazards and/or exposure to humans and the environment. Consequently, the EFSA PPR Panel was mandated to advise on the likelihood that body of evidence would constitute proof of serious risks to humans or the environment. Therefore, the EFSA PPR Panel evaluated the likelihood of these studies indicating new or higher hazards and exposure to humans and the environment compared to previous EU assessments.A stepwise methodology was designed, including: (i) the initial screening; (ii) the data extraction and critical appraisal based on the principles of OHAT/NTP; (iii) the weight of evidence, including consideration of the previous EU assessments; (iv) the uncertainty analysis, followed, whenever relevant, by an expert knowledge elicitation process. For human health, no conclusive evidence of higher hazards compared to previous assessment was found for genotoxicity, developmental toxicity, neurotoxicity including developmental neurotoxicity and immunotoxicity. However, due to the lack of adequate assessment of the current data set, the PPR Panel recommends conducting an assessment of endocrine disrupting properties for acetamiprid in line with EFSA/ECHA guidance document for the identification of endocrine disruptors. For environment, no conclusive, robust evidence of higher hazards compared to the previous assessment was found for birds, aquatic organisms, bees and soil organisms. However, the potential of high inter‐species sensitivity of birds and bees towards acetamiprid requires further consideration. John Wiley and Sons Inc. 2022-01-24 /pmc/articles/PMC8784984/ /pubmed/35106090 http://dx.doi.org/10.2903/j.efsa.2022.7031 Text en © 2022 European Food Safety Authority. EFSA Journal published by John Wiley and Sons Ltd on behalf of European Food Safety Authority. https://creativecommons.org/licenses/by-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nd/4.0/ (https://creativecommons.org/licenses/by-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited and no modifications or adaptations are made. |
spellingShingle | Statement Hernandez Jerez, Antonio Adriaanse, Paulien Berny, Philippe Coja, Tamara Duquesne, Sabine Focks, Andreas Marinovich, Marina Millet, Maurice Pelkonen, Olavi Pieper, Silvia Tiktak, Aaldrik Topping, Christopher Widenfalk, Anneli Wilks, Martin Wolterink, Gerrit Rundlöf, Maj Ippolito, Alessio Linguadoca, Alberto Martino, Laura Panzarea, Martina Terron, Andrea Aldrich, Annette Statement on the active substance acetamiprid |
title | Statement on the active substance acetamiprid |
title_full | Statement on the active substance acetamiprid |
title_fullStr | Statement on the active substance acetamiprid |
title_full_unstemmed | Statement on the active substance acetamiprid |
title_short | Statement on the active substance acetamiprid |
title_sort | statement on the active substance acetamiprid |
topic | Statement |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8784984/ https://www.ncbi.nlm.nih.gov/pubmed/35106090 http://dx.doi.org/10.2903/j.efsa.2022.7031 |
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