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Intracranial aneurysm treatment with WEB and adjunctive stent: preliminary evaluation in a single-center series

BACKGROUND: Intrasaccular flow disruption with WEB is a safe and efficacious technique that has significantly changed endovascular management of wide-neck bifurcation aneurysms (WNBAs). Use of stent in combination with WEB is occasionally required. We analyzed the frequency of use, indications, safe...

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Autores principales: Sahnoun, Maher, Soize, Sébastien, Manceau, Pierre-François, Gelmini, Christophe, Pierot, Laurent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8785053/
https://www.ncbi.nlm.nih.gov/pubmed/33785641
http://dx.doi.org/10.1136/neurintsurg-2021-017379
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author Sahnoun, Maher
Soize, Sébastien
Manceau, Pierre-François
Gelmini, Christophe
Pierot, Laurent
author_facet Sahnoun, Maher
Soize, Sébastien
Manceau, Pierre-François
Gelmini, Christophe
Pierot, Laurent
author_sort Sahnoun, Maher
collection PubMed
description BACKGROUND: Intrasaccular flow disruption with WEB is a safe and efficacious technique that has significantly changed endovascular management of wide-neck bifurcation aneurysms (WNBAs). Use of stent in combination with WEB is occasionally required. We analyzed the frequency of use, indications, safety, and efficacy of the WEB–stent combination. METHODS: All aneurysms treated with WEB and stent were extracted from a prospectively maintained database. Patient and aneurysm characteristics, complications, and anatomical results were independently analyzed by a physician independent of the procedures. RESULTS: From June 2011 to January 2020, 152 patients with 157 aneurysms were treated with WEB. Of these, 17/152 patients (11.2%) with 19/157 aneurysms (12.1%) were treated with WEB device and stent. Indications were very wide neck with a branch emerging from the neck in 1/19 (5.2%) aneurysms and WEB protrusion in 18/19 (94.7%). At 1 month, no morbimortality was reported. At 6 months, anatomical results were complete aneurysm occlusion in 15/17 aneurysms (88.2%), neck remnant in 1/17 (5.9%), and aneurysm remnant in 1/17 (5.9%). At 12 months, there was complete aneurysm occlusion in 13/14 aneurysms (92.9%) and neck remnant in 1/14 (7.1%). CONCLUSIONS: Combining WEB and stent is a therapeutic strategy to manage WNBA. In our series, this combination was used in 11.2% of patients treated with WEB, resulting in no morbidity or mortality with a high efficacy at 6 and 12 months (complete aneurysm occlusion in 88.2% and 92.9%, respectively).
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spelling pubmed-87850532022-02-04 Intracranial aneurysm treatment with WEB and adjunctive stent: preliminary evaluation in a single-center series Sahnoun, Maher Soize, Sébastien Manceau, Pierre-François Gelmini, Christophe Pierot, Laurent J Neurointerv Surg New Devices and Techniques BACKGROUND: Intrasaccular flow disruption with WEB is a safe and efficacious technique that has significantly changed endovascular management of wide-neck bifurcation aneurysms (WNBAs). Use of stent in combination with WEB is occasionally required. We analyzed the frequency of use, indications, safety, and efficacy of the WEB–stent combination. METHODS: All aneurysms treated with WEB and stent were extracted from a prospectively maintained database. Patient and aneurysm characteristics, complications, and anatomical results were independently analyzed by a physician independent of the procedures. RESULTS: From June 2011 to January 2020, 152 patients with 157 aneurysms were treated with WEB. Of these, 17/152 patients (11.2%) with 19/157 aneurysms (12.1%) were treated with WEB device and stent. Indications were very wide neck with a branch emerging from the neck in 1/19 (5.2%) aneurysms and WEB protrusion in 18/19 (94.7%). At 1 month, no morbimortality was reported. At 6 months, anatomical results were complete aneurysm occlusion in 15/17 aneurysms (88.2%), neck remnant in 1/17 (5.9%), and aneurysm remnant in 1/17 (5.9%). At 12 months, there was complete aneurysm occlusion in 13/14 aneurysms (92.9%) and neck remnant in 1/14 (7.1%). CONCLUSIONS: Combining WEB and stent is a therapeutic strategy to manage WNBA. In our series, this combination was used in 11.2% of patients treated with WEB, resulting in no morbidity or mortality with a high efficacy at 6 and 12 months (complete aneurysm occlusion in 88.2% and 92.9%, respectively). BMJ Publishing Group 2022-02 2021-03-30 /pmc/articles/PMC8785053/ /pubmed/33785641 http://dx.doi.org/10.1136/neurintsurg-2021-017379 Text en © Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) .
spellingShingle New Devices and Techniques
Sahnoun, Maher
Soize, Sébastien
Manceau, Pierre-François
Gelmini, Christophe
Pierot, Laurent
Intracranial aneurysm treatment with WEB and adjunctive stent: preliminary evaluation in a single-center series
title Intracranial aneurysm treatment with WEB and adjunctive stent: preliminary evaluation in a single-center series
title_full Intracranial aneurysm treatment with WEB and adjunctive stent: preliminary evaluation in a single-center series
title_fullStr Intracranial aneurysm treatment with WEB and adjunctive stent: preliminary evaluation in a single-center series
title_full_unstemmed Intracranial aneurysm treatment with WEB and adjunctive stent: preliminary evaluation in a single-center series
title_short Intracranial aneurysm treatment with WEB and adjunctive stent: preliminary evaluation in a single-center series
title_sort intracranial aneurysm treatment with web and adjunctive stent: preliminary evaluation in a single-center series
topic New Devices and Techniques
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8785053/
https://www.ncbi.nlm.nih.gov/pubmed/33785641
http://dx.doi.org/10.1136/neurintsurg-2021-017379
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