COVID-19 in children with haematological malignancies

BACKGROUND: Children with cancer are not at increased risk of severe SARS-CoV-2 infection; however, adults with haematological malignancies have increased risk of severe infections compared with non-haematological malignancies. METHODS: We compared patients with haematological and non-haematological...

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Detalles Bibliográficos
Autores principales: Millen, Gerard Cathal, Arnold, Roland, Cazier, Jean-Baptiste, Curley, Helen, Feltbower, Richard, Gamble, Ashley, Glaser, Adam, Grundy, Richard G, Kirton, Laura, Lee, Lennard Y W, McCabe, Martin G, Palles, Claire, Phillips, Bob, Stiller, Charles A, Varnai, Csilla, Kearns, Pamela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8785070/
https://www.ncbi.nlm.nih.gov/pubmed/34301621
http://dx.doi.org/10.1136/archdischild-2021-322062
Descripción
Sumario:BACKGROUND: Children with cancer are not at increased risk of severe SARS-CoV-2 infection; however, adults with haematological malignancies have increased risk of severe infections compared with non-haematological malignancies. METHODS: We compared patients with haematological and non-haematological malignancies enrolled in the UK Paediatric Coronavirus Cancer Monitoring Project between 12 March 2020 and 16 February 2021. Children who received stem cell transplantation were excluded. RESULTS: Only 2/62 patients with haematological malignancy had severe/critical infections, with an OR of 0.5 for patients with haematological compared with non-haematological malignancies. INTERPRETATION: Children with haematological malignancies are at no greater risk of severe SARS-CoV-2 infection than those with non-haematological malignancies.

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