Ensuring Sufficient Trough Plasma Concentrations for Broad-Spectrum Beta-Lactam Antibiotics in Children With Malignancies: Beware of Augmented Renal Clearance!

Introduction: Broad-spectrum beta-lactams are commonly prescribed for empirical or selective treatment of bacterial infections in children with malignancies. In the immunocompromised, appropriate concentration exposure is crucial to ensure antimicrobial efficacy. Augmented renal clearance (ARC) is i...

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Detalles Bibliográficos
Autores principales: André, Pascal, Diezi, Léonore, Dao, Kim, Crisinel, Pierre Alex, Rothuizen, Laura E., Chtioui, Haithem, Decosterd, Laurent Arthur, Diezi, Manuel, Asner, Sandra, Buclin, Thierry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pediatrics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8785252/
https://www.ncbi.nlm.nih.gov/pubmed/35083184
http://dx.doi.org/10.3389/fped.2021.768438

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