Histone H4 induces heparan sulfate degradation by activating heparanase in chlorine gas-induced acute respiratory distress syndrome

BACKGROUND: Heparan sulfate (HS) degradation mediates pulmonary endothelial hyper-permeability and acute pulmonary edema during acute respiratory distress syndrome (ARDS). The aim of this study was to examine whether histone H4 induced HS degradation by activating heparanase (HPSE) in chlorine gas (...

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Detalles Bibliográficos
Autores principales: Zhang, Yanlin, Xu, Fei, Guan, Li, Chen, Ming, Zhao, Yiran, Guo, Lixia, Li, Xiao, Zheng, Yimu, Gao, Ai, Li, Shuqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8785471/
https://www.ncbi.nlm.nih.gov/pubmed/35073921
http://dx.doi.org/10.1186/s12931-022-01932-y

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