SMARCA5 interacts with NUP98-NSD1 oncofusion protein and sustains hematopoietic cells transformation

BACKGROUND: Acute myeloid leukemia (AML) is characterized by accumulation of aberrantly differentiated hematopoietic myeloid progenitor cells. The karyotyping-silent NUP98-NSD1 fusion is a molecular hallmark of pediatric AML and is associated with the activating FLT3-ITD mutation in > 70% of the...

Descripción completa

Detalles Bibliográficos
Autores principales: Jevtic, Zivojin, Matafora, Vittoria, Casagrande, Francesca, Santoro, Fabio, Minucci, Saverio, Garre’, Massimilliano, Rasouli, Milad, Heidenreich, Olaf, Musco, Giovanna, Schwaller, Jürg, Bachi, Angela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8785526/
https://www.ncbi.nlm.nih.gov/pubmed/35073946
http://dx.doi.org/10.1186/s13046-022-02248-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8785526/
https://www.ncbi.nlm.nih.gov/pubmed/35073946
http://dx.doi.org/10.1186/s13046-022-02248-x

Ejemplares similares