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SMARCA5 interacts with NUP98-NSD1 oncofusion protein and sustains hematopoietic cells transformation

BACKGROUND: Acute myeloid leukemia (AML) is characterized by accumulation of aberrantly differentiated hematopoietic myeloid progenitor cells. The karyotyping-silent NUP98-NSD1 fusion is a molecular hallmark of pediatric AML and is associated with the activating FLT3-ITD mutation in > 70% of the...

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Detalles Bibliográficos
Autores principales:	Jevtic, Zivojin, Matafora, Vittoria, Casagrande, Francesca, Santoro, Fabio, Minucci, Saverio, Garre’, Massimilliano, Rasouli, Milad, Heidenreich, Olaf, Musco, Giovanna, Schwaller, Jürg, Bachi, Angela
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8785526/ https://www.ncbi.nlm.nih.gov/pubmed/35073946 http://dx.doi.org/10.1186/s13046-022-02248-x

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