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A Thrombomodulin Promoter Gene Polymorphism, rs2239562, Influences Both Susceptibility to and Outcome of Sepsis

Objective: Disseminated intravascular coagulation plays a key role in the pathophysiology of sepsis. Thrombomodulin is essential in the protein C system of coagulation cascade, and functional polymorphisms influence the human thrombomodulin gene (THBD). Therefore, we conducted a multicenter study to...

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Detalles Bibliográficos
Autores principales:	Watanabe, Eizo, Takasu, Osamu, Teratake, Youichi, Sakamoto, Teruo, Ikeda, Toshiaki, Kotani, Joji, Kitamura, Nobuya, Ohmori, Masaaki, Teratani, Ayako, Honda, Goichi, Hatano, Masahiko, Mayer, Benjamin, Schneider, E. Marion, Oda, Shigeto
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8785550/ https://www.ncbi.nlm.nih.gov/pubmed/35083232 http://dx.doi.org/10.3389/fmed.2021.762198

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