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Gut microbiota–derived metabolite 3-idoleacetic acid together with LPS induces IL-35(+) B cell generation

BACKGROUND: IL-35–producing Bregs and Treg cells critically regulate chronic illnesses worldwide via mechanisms related to disrupting the gut microbiota composition. However, whether the gut microbiota regulates these IL-35(+) cells remains elusive. We herein investigated the regulatory effects of t...

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Detalles Bibliográficos
Autores principales: Su, Xiaomin, Zhang, Minying, Qi, Houbao, Gao, Yunhuan, Yang, Yazheng, Yun, Huan, Zhang, Qianjing, Yang, Xiaorong, Zhang, Yuan, He, Jiangshan, Fan, Yaqi, Wang, Yuxue, Guo, Pei, Zhang, Chunze, Yang, Rongcun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8785567/
https://www.ncbi.nlm.nih.gov/pubmed/35074011
http://dx.doi.org/10.1186/s40168-021-01205-8