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The (Lack of) DNA Double-Strand Break Repair Pathway Choice During V(D)J Recombination

DNA double-strand breaks (DSBs) are highly toxic lesions that can be mended via several DNA repair pathways. Multiple factors can influence the choice and the restrictiveness of repair towards a given pathway in order to warrant the maintenance of genome integrity. During V(D)J recombination, RAG-in...

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Detalles Bibliográficos
Autores principales: Libri, Alice, Marton, Timea, Deriano, Ludovic
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8785701/
https://www.ncbi.nlm.nih.gov/pubmed/35082840
http://dx.doi.org/10.3389/fgene.2021.823943

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