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Bidirectional associations between cognitive functions and walking performance among middle-aged women

OBJECTIVE: This study investigated whether (1) cognitive functions change after the transition from the perimenopausal to the postmenopausal stage, (2) cognitive functions and walking are associated in middle-aged women, and (3) cognitive functions assessed in perimenopause are associated with walki...

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Autores principales: Tirkkonen, Anna, Kekäläinen, Tiia, Aukee, Pauliina, Kujala, Urho M., Laakkonen, Eija K., Kokko, Katja, Sipilä, Sarianna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8785773/
https://www.ncbi.nlm.nih.gov/pubmed/34930867
http://dx.doi.org/10.1097/GME.0000000000001896
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author Tirkkonen, Anna
Kekäläinen, Tiia
Aukee, Pauliina
Kujala, Urho M.
Laakkonen, Eija K.
Kokko, Katja
Sipilä, Sarianna
author_facet Tirkkonen, Anna
Kekäläinen, Tiia
Aukee, Pauliina
Kujala, Urho M.
Laakkonen, Eija K.
Kokko, Katja
Sipilä, Sarianna
author_sort Tirkkonen, Anna
collection PubMed
description OBJECTIVE: This study investigated whether (1) cognitive functions change after the transition from the perimenopausal to the postmenopausal stage, (2) cognitive functions and walking are associated in middle-aged women, and (3) cognitive functions assessed in perimenopause are associated with walking after reaching the postmenopause or vice versa. METHODS: In total, 342 women, categorized as early (n = 158) or late perimenopausal (n = 184), were included in the study and followed up until postmenopausal. Psychomotor speed, executive functions related to set-shifting and updating, working memory, and visual memory were assessed. Walking was assessed with walking speed, walking distance, and dual-task cost in walking speed. Data was analyzed using the paired-samples t test, Wilcoxon signed rank test, multiple linear regression analysis, and structural equation modeling. RESULTS: We found small but significant improvements in psychomotor speed (P = 0.01) and working memory (P < 0.001) among early perimenopausal and in psychomotor speed (P = 0.001), set-shifting (P = 0.02), visual memory (P = 0.002), and working memory (P < 0.001) among late perimenopausal women after the transition from peri- to postmenopause. Walking speed (β = 0.264, P = 0.001) and dual-task cost (β = 0.160, P = 0.03) were associated with updating, and walking distance was associated with updating and set-shifting (β = 0.198, P = 0.02, β=−0.178 P = 0.04 respectively) among the late perimenopausal women. We found no longitudinal associations between cognitive functions and walking. CONCLUSION: Cognitive performance remained unchanged or improved after reaching postmenopause. Cognitive functions and walking were associated during the late perimenopause, but the association depended on the cognitive process and nature of the physical task. Cognitive performance was not associated with walking after reaching postmenopause or vice versa.
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spelling pubmed-87857732022-01-31 Bidirectional associations between cognitive functions and walking performance among middle-aged women Tirkkonen, Anna Kekäläinen, Tiia Aukee, Pauliina Kujala, Urho M. Laakkonen, Eija K. Kokko, Katja Sipilä, Sarianna Menopause Original Studies OBJECTIVE: This study investigated whether (1) cognitive functions change after the transition from the perimenopausal to the postmenopausal stage, (2) cognitive functions and walking are associated in middle-aged women, and (3) cognitive functions assessed in perimenopause are associated with walking after reaching the postmenopause or vice versa. METHODS: In total, 342 women, categorized as early (n = 158) or late perimenopausal (n = 184), were included in the study and followed up until postmenopausal. Psychomotor speed, executive functions related to set-shifting and updating, working memory, and visual memory were assessed. Walking was assessed with walking speed, walking distance, and dual-task cost in walking speed. Data was analyzed using the paired-samples t test, Wilcoxon signed rank test, multiple linear regression analysis, and structural equation modeling. RESULTS: We found small but significant improvements in psychomotor speed (P = 0.01) and working memory (P < 0.001) among early perimenopausal and in psychomotor speed (P = 0.001), set-shifting (P = 0.02), visual memory (P = 0.002), and working memory (P < 0.001) among late perimenopausal women after the transition from peri- to postmenopause. Walking speed (β = 0.264, P = 0.001) and dual-task cost (β = 0.160, P = 0.03) were associated with updating, and walking distance was associated with updating and set-shifting (β = 0.198, P = 0.02, β=−0.178 P = 0.04 respectively) among the late perimenopausal women. We found no longitudinal associations between cognitive functions and walking. CONCLUSION: Cognitive performance remained unchanged or improved after reaching postmenopause. Cognitive functions and walking were associated during the late perimenopause, but the association depended on the cognitive process and nature of the physical task. Cognitive performance was not associated with walking after reaching postmenopause or vice versa. Lippincott Williams & Wilkins 2021-12-20 /pmc/articles/PMC8785773/ /pubmed/34930867 http://dx.doi.org/10.1097/GME.0000000000001896 Text en Copyright © 2021 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of The North American Menopause Society. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc-nd/4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/)
spellingShingle Original Studies
Tirkkonen, Anna
Kekäläinen, Tiia
Aukee, Pauliina
Kujala, Urho M.
Laakkonen, Eija K.
Kokko, Katja
Sipilä, Sarianna
Bidirectional associations between cognitive functions and walking performance among middle-aged women
title Bidirectional associations between cognitive functions and walking performance among middle-aged women
title_full Bidirectional associations between cognitive functions and walking performance among middle-aged women
title_fullStr Bidirectional associations between cognitive functions and walking performance among middle-aged women
title_full_unstemmed Bidirectional associations between cognitive functions and walking performance among middle-aged women
title_short Bidirectional associations between cognitive functions and walking performance among middle-aged women
title_sort bidirectional associations between cognitive functions and walking performance among middle-aged women
topic Original Studies
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8785773/
https://www.ncbi.nlm.nih.gov/pubmed/34930867
http://dx.doi.org/10.1097/GME.0000000000001896
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