Effects of Wood Smoke Constituents on Mucin Gene Expression in Mice and Human Airway Epithelial Cells and on Nasal Epithelia of Subjects with a Susceptibility Gene Variant in Tp53

BACKGROUND: Exposure to wood smoke (WS) increases the risk for chronic bronchitis more than exposure to cigarette smoke (CS), but the underlying mechanisms are unclear. OBJECTIVE: The effect of WS and CS on mucous cell hyperplasia in mice and in human primary airway epithelial cells (AECs) was compa...

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Detalles Bibliográficos
Autores principales: Tassew, Dereje, Fort, Susan, Mebratu, Yohannes, McDonald, Jacob, Chu, Hong Wei, Petersen, Hans, Tesfaigzi, Yohannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Environmental Health Perspectives 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8785869/
https://www.ncbi.nlm.nih.gov/pubmed/35072516
http://dx.doi.org/10.1289/EHP9446

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