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Personalized endoprostheses for the proximal humerus and scapulohumeral joint in dogs: Biomechanical study of the muscles’ contributions during locomotion

Osteosarcoma represents one of the most common bone tumours in dogs. It commonly occurs in the proximal humerus, the most affected anatomic site. Until recently, amputation or limb-sparing surgery leading to an arthrodesis coupled with chemotherapy were the only available treatments, but they often...

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Autores principales: Le Bras, Linh-Aurore, Timercan, Anatolie, Llido, Marie, Petit, Yvan, Seguin, Bernard, Lussier, Bertrand, Brailovski, Vladimir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8786195/
https://www.ncbi.nlm.nih.gov/pubmed/35073361
http://dx.doi.org/10.1371/journal.pone.0262863
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author Le Bras, Linh-Aurore
Timercan, Anatolie
Llido, Marie
Petit, Yvan
Seguin, Bernard
Lussier, Bertrand
Brailovski, Vladimir
author_facet Le Bras, Linh-Aurore
Timercan, Anatolie
Llido, Marie
Petit, Yvan
Seguin, Bernard
Lussier, Bertrand
Brailovski, Vladimir
author_sort Le Bras, Linh-Aurore
collection PubMed
description Osteosarcoma represents one of the most common bone tumours in dogs. It commonly occurs in the proximal humerus, the most affected anatomic site. Until recently, amputation or limb-sparing surgery leading to an arthrodesis coupled with chemotherapy were the only available treatments, but they often lead to complications, reduced mobility and highly impact dog’s quality of life. Prototypes of both articulated and monobloc (no mobility) patient-specific endoprostheses have been designed to spare the limb afflicted with osteosarcoma of the proximal humerus. This study focuses on the biomechanical effects of endoprostheses and shoulder muscle kinematics. For each of the endoprosthesis designs, a minimal number of muscles needed to ensure stability and a certain degree of joint movement during walking is sought. A quasi-static study based on an optimization method, the minimization of the sum of maximal muscle stresses, was carried out to assess the contribution of each muscle to the shoulder function. The identification of the most important muscles and their impact on the kinematics of the prosthetic joint lead to an improvement of the endoprosthesis design relevance and implantation feasibility.
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spelling pubmed-87861952022-01-25 Personalized endoprostheses for the proximal humerus and scapulohumeral joint in dogs: Biomechanical study of the muscles’ contributions during locomotion Le Bras, Linh-Aurore Timercan, Anatolie Llido, Marie Petit, Yvan Seguin, Bernard Lussier, Bertrand Brailovski, Vladimir PLoS One Research Article Osteosarcoma represents one of the most common bone tumours in dogs. It commonly occurs in the proximal humerus, the most affected anatomic site. Until recently, amputation or limb-sparing surgery leading to an arthrodesis coupled with chemotherapy were the only available treatments, but they often lead to complications, reduced mobility and highly impact dog’s quality of life. Prototypes of both articulated and monobloc (no mobility) patient-specific endoprostheses have been designed to spare the limb afflicted with osteosarcoma of the proximal humerus. This study focuses on the biomechanical effects of endoprostheses and shoulder muscle kinematics. For each of the endoprosthesis designs, a minimal number of muscles needed to ensure stability and a certain degree of joint movement during walking is sought. A quasi-static study based on an optimization method, the minimization of the sum of maximal muscle stresses, was carried out to assess the contribution of each muscle to the shoulder function. The identification of the most important muscles and their impact on the kinematics of the prosthetic joint lead to an improvement of the endoprosthesis design relevance and implantation feasibility. Public Library of Science 2022-01-24 /pmc/articles/PMC8786195/ /pubmed/35073361 http://dx.doi.org/10.1371/journal.pone.0262863 Text en © 2022 Le Bras et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Le Bras, Linh-Aurore
Timercan, Anatolie
Llido, Marie
Petit, Yvan
Seguin, Bernard
Lussier, Bertrand
Brailovski, Vladimir
Personalized endoprostheses for the proximal humerus and scapulohumeral joint in dogs: Biomechanical study of the muscles’ contributions during locomotion
title Personalized endoprostheses for the proximal humerus and scapulohumeral joint in dogs: Biomechanical study of the muscles’ contributions during locomotion
title_full Personalized endoprostheses for the proximal humerus and scapulohumeral joint in dogs: Biomechanical study of the muscles’ contributions during locomotion
title_fullStr Personalized endoprostheses for the proximal humerus and scapulohumeral joint in dogs: Biomechanical study of the muscles’ contributions during locomotion
title_full_unstemmed Personalized endoprostheses for the proximal humerus and scapulohumeral joint in dogs: Biomechanical study of the muscles’ contributions during locomotion
title_short Personalized endoprostheses for the proximal humerus and scapulohumeral joint in dogs: Biomechanical study of the muscles’ contributions during locomotion
title_sort personalized endoprostheses for the proximal humerus and scapulohumeral joint in dogs: biomechanical study of the muscles’ contributions during locomotion
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8786195/
https://www.ncbi.nlm.nih.gov/pubmed/35073361
http://dx.doi.org/10.1371/journal.pone.0262863
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