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Mucociliary Transport Deficiency and Disease Progression in Syrian Hamsters with SARS-CoV-2 Infection

Substantial clinical evidence supports the notion that ciliary function in the airways plays an important role in COVID-19 pathogenesis. Although ciliary damage has been observed in both in vitro and in vivo models, consequent impaired mucociliary transport (MCT) remains unknown for the intact MCT a...

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Detalles Bibliográficos
Autores principales: Li, Qian, Vijaykumar, Kadambari, Philips, Scott E, Hussain, Shah S, Huynh, Van N, Fernandez-Petty, Courtney M, Lever, Jacelyn E Peabody, Foote, Jeremy B, Ren, Janna, Campos-Gómez, Javier, Daya, Farah Abou, Hubbs, Nathaniel W, Kim, Harrison, Onuoha, Ezinwanne, Boitet, Evan R, Fu, Lianwu, Leung, Hui Min, Yu, Linhui, Detchemendy, Thomas W, Schaefers, Levi T, Tipper, Jennifer L, Edwards, Lloyd J, Leal, Sixto M, Harrod, Kevin S, Tearney, Guillermo J, Rowe, Steven M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8786228/
https://www.ncbi.nlm.nih.gov/pubmed/35075457
http://dx.doi.org/10.1101/2022.01.16.476016