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Serine acetyltransferase from Neisseria gonorrhoeae; structural and biochemical basis of inhibition

Serine acetyltransferase (SAT) catalyzes the first step in the two-step pathway to synthesize l-cysteine in bacteria and plants. SAT synthesizes O-acetylserine from substrates l-serine and acetyl coenzyme A and is a key enzyme for regulating cellular cysteine levels by feedback inhibition of l-cyste...

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Detalles Bibliográficos
Autores principales: Oldham, Keely E. A., Prentice, Erica J., Summers, Emma L., Hicks, Joanna L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2022
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8786284/
https://www.ncbi.nlm.nih.gov/pubmed/34890451
http://dx.doi.org/10.1042/BCJ20210564