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Controlled power: how biology manages succinate-driven energy release

Oxidation of succinate by mitochondria can generate a higher protonmotive force (pmf) than can oxidation of NADH-linked substrates. Fundamentally, this is because of differences in redox potentials and gearing. Biology adds kinetic constraints that tune the oxidation of NADH and succinate to ensure...

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Detalles Bibliográficos
Autores principales: Mookerjee, Shona A., Gerencser, Akos A., Watson, Mark A., Brand, Martin D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8786295/
https://www.ncbi.nlm.nih.gov/pubmed/34882231
http://dx.doi.org/10.1042/BST20211032