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Controlled power: how biology manages succinate-driven energy release
Oxidation of succinate by mitochondria can generate a higher protonmotive force (pmf) than can oxidation of NADH-linked substrates. Fundamentally, this is because of differences in redox potentials and gearing. Biology adds kinetic constraints that tune the oxidation of NADH and succinate to ensure...
Autores principales: | Mookerjee, Shona A., Gerencser, Akos A., Watson, Mark A., Brand, Martin D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8786295/ https://www.ncbi.nlm.nih.gov/pubmed/34882231 http://dx.doi.org/10.1042/BST20211032 |
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