SNX9-induced membrane tubulation regulates CD28 cluster stability and signalling

T cell activation requires engagement of a cognate antigen by the T cell receptor (TCR) and the co-stimulatory signal of CD28. Both TCR and CD28 aggregate into clusters at the plasma membrane of activated T cells. While the role of TCR clustering in T cell activation has been extensively investigate...

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Detalles Bibliográficos
Autores principales: Ecker, Manuela, Schregle, Richard, Kapoor-Kaushik, Natasha, Rossatti, Pascal, Betzler, Verena M, Kempe, Daryan, Biro, Maté, Ariotti, Nicholas, Redpath, Gregory MI, Rossy, Jeremie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8786313/
https://www.ncbi.nlm.nih.gov/pubmed/35050850
http://dx.doi.org/10.7554/eLife.67550

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