Cardiac Involvement by Human Herpesvirus 8-Positive Diffuse Large B-Cell Lymphoma: An Unusual Presentation in a Patient with Human Immunodeficiency Virus

Human immunodeficiency virus (HIV) infection predisposes patients to the development of lymphomas, both due to immune suppression and coinfection with viruses with oncogenic potential. Coinfection with human herpesvirus 8 (HHV8) in particular has been associated with the development of aggressive ly...

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Autores principales: Fenu, Elena M., Beaty, Michael W., O'Neill, Tiffany E., O'Neill, Stacey S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8786529/
https://www.ncbi.nlm.nih.gov/pubmed/35083089
http://dx.doi.org/10.1155/2022/1298121
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author Fenu, Elena M.
Beaty, Michael W.
O'Neill, Tiffany E.
O'Neill, Stacey S.
author_facet Fenu, Elena M.
Beaty, Michael W.
O'Neill, Tiffany E.
O'Neill, Stacey S.
author_sort Fenu, Elena M.
collection PubMed
description Human immunodeficiency virus (HIV) infection predisposes patients to the development of lymphomas, both due to immune suppression and coinfection with viruses with oncogenic potential. Coinfection with human herpesvirus 8 (HHV8) in particular has been associated with the development of aggressive lymphomas, including primary effusion lymphoma and diffuse large B-cell lymphoma (DLBCL). Herein, we report an unusual case of HHV8-positive DLBCL with extensive cardiac involvement which was diagnosed at autopsy in a patient with long-standing untreated HIV infection.
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spelling pubmed-87865292022-01-25 Cardiac Involvement by Human Herpesvirus 8-Positive Diffuse Large B-Cell Lymphoma: An Unusual Presentation in a Patient with Human Immunodeficiency Virus Fenu, Elena M. Beaty, Michael W. O'Neill, Tiffany E. O'Neill, Stacey S. Case Rep Pathol Case Report Human immunodeficiency virus (HIV) infection predisposes patients to the development of lymphomas, both due to immune suppression and coinfection with viruses with oncogenic potential. Coinfection with human herpesvirus 8 (HHV8) in particular has been associated with the development of aggressive lymphomas, including primary effusion lymphoma and diffuse large B-cell lymphoma (DLBCL). Herein, we report an unusual case of HHV8-positive DLBCL with extensive cardiac involvement which was diagnosed at autopsy in a patient with long-standing untreated HIV infection. Hindawi 2022-01-17 /pmc/articles/PMC8786529/ /pubmed/35083089 http://dx.doi.org/10.1155/2022/1298121 Text en Copyright © 2022 Elena M. Fenu et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Fenu, Elena M.
Beaty, Michael W.
O'Neill, Tiffany E.
O'Neill, Stacey S.
Cardiac Involvement by Human Herpesvirus 8-Positive Diffuse Large B-Cell Lymphoma: An Unusual Presentation in a Patient with Human Immunodeficiency Virus
title Cardiac Involvement by Human Herpesvirus 8-Positive Diffuse Large B-Cell Lymphoma: An Unusual Presentation in a Patient with Human Immunodeficiency Virus
title_full Cardiac Involvement by Human Herpesvirus 8-Positive Diffuse Large B-Cell Lymphoma: An Unusual Presentation in a Patient with Human Immunodeficiency Virus
title_fullStr Cardiac Involvement by Human Herpesvirus 8-Positive Diffuse Large B-Cell Lymphoma: An Unusual Presentation in a Patient with Human Immunodeficiency Virus
title_full_unstemmed Cardiac Involvement by Human Herpesvirus 8-Positive Diffuse Large B-Cell Lymphoma: An Unusual Presentation in a Patient with Human Immunodeficiency Virus
title_short Cardiac Involvement by Human Herpesvirus 8-Positive Diffuse Large B-Cell Lymphoma: An Unusual Presentation in a Patient with Human Immunodeficiency Virus
title_sort cardiac involvement by human herpesvirus 8-positive diffuse large b-cell lymphoma: an unusual presentation in a patient with human immunodeficiency virus
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8786529/
https://www.ncbi.nlm.nih.gov/pubmed/35083089
http://dx.doi.org/10.1155/2022/1298121
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