Type I interferons and SARS-CoV-2: from cells to organisms

Type I interferons (IFNs) have broad and potent antiviral activity. We review the interplay between type I IFNs and SARS-CoV-2. Human cells infected with SARS-CoV-2 in vitro produce low levels of type I IFNs, and SARS-CoV-2 proteins can inhibit various steps in type I IFN production and response. Ex...

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Detalles Bibliográficos
Autores principales: Bastard, Paul, Zhang, Qian, Zhang, Shen-Ying, Jouanguy, Emmanuelle, Casanova, Jean-Laurent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier Ltd. 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8786610/
https://www.ncbi.nlm.nih.gov/pubmed/35149239
http://dx.doi.org/10.1016/j.coi.2022.01.003

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