The Impact of Age and BMI on the VWF/ADAMTS13 Axis and Simultaneous Thrombin and Plasmin Generation in Hospitalized COVID-19 Patients

Aging and obesity independently contribute toward an endothelial dysfunction that results in an imbalanced VWF to ADAMTS13 ratio. In addition, plasma thrombin and plasmin generation are elevated and reduced, respectively, with increasing age and also with increasing body mass index (BMI). The severi...

Descripción completa

Detalles Bibliográficos
Autores principales: Thangaraju, Kiruphagaran, Katneni, Upendra, Akpan, Imo J., Tanaka, Kenichi, Thomas, Tiffany, Setua, Saini, Reisz, Julie A., Cendali, Francesca, Gamboni, Fabia, Nemkov, Travis, Kahn, Stacie, Wei, Alexander Z., Valk, Jacob E., Hudson, Krystalyn E., Roh, David J., Moriconi, Chiara, Zimring, James C., D'Alessandro, Angelo, Spitalnik, Steven L., Francis, Richard O., Buehler, Paul W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8786628/
https://www.ncbi.nlm.nih.gov/pubmed/35087853
http://dx.doi.org/10.3389/fmed.2021.817305

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8786628/
https://www.ncbi.nlm.nih.gov/pubmed/35087853
http://dx.doi.org/10.3389/fmed.2021.817305

Ejemplares similares