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The influence of preconditioning with low dose of LPS on paraquat-induced neurotoxicity, microglia activation and expression of α-synuclein and synphilin-1 in the dopaminergic system

BACKGROUND: Prolonged inflammation, oxidative stress, and protein aggregation are important factors contributing to Parkinson’s disease (PD) pathology. A known ROS generator, pesticide paraquat (PQ), was indicated as an environmental substance potentially increasing the incidence of PD and is used t...

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Detalles Bibliográficos
Autores principales: Kuter, Katarzyna Z., Śmiałowska, Maria, Ossowska, Krystyna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8786770/
https://www.ncbi.nlm.nih.gov/pubmed/34762280
http://dx.doi.org/10.1007/s43440-021-00340-1