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The reference liver—CYP450 and UGT enzymes in healthy donor and metastatic livers: the impact of genotype
BACKGROUND: Hepatic enzymes involved in drug metabolism vary markedly in expression, abundance and activity, which affects individual susceptibility to drugs and toxicants. The present study aimed to compare mRNA expression and protein abundance of the most pharmacologically relevant drug-metabolizi...
Autores principales: | Kurzawski, Mateusz, Szeląg-Pieniek, Sylwia, Łapczuk-Romańska, Joanna, Wrzesiński, Maciej, Oswald, Stefan, Droździk, Marek |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8786777/ https://www.ncbi.nlm.nih.gov/pubmed/34741761 http://dx.doi.org/10.1007/s43440-021-00337-w |
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