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The reference liver—CYP450 and UGT enzymes in healthy donor and metastatic livers: the impact of genotype

BACKGROUND: Hepatic enzymes involved in drug metabolism vary markedly in expression, abundance and activity, which affects individual susceptibility to drugs and toxicants. The present study aimed to compare mRNA expression and protein abundance of the most pharmacologically relevant drug-metabolizi...

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Detalles Bibliográficos
Autores principales: Kurzawski, Mateusz, Szeląg-Pieniek, Sylwia, Łapczuk-Romańska, Joanna, Wrzesiński, Maciej, Oswald, Stefan, Droździk, Marek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8786777/
https://www.ncbi.nlm.nih.gov/pubmed/34741761
http://dx.doi.org/10.1007/s43440-021-00337-w

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