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NME1 Protects Against Neurotoxin-, α-Synuclein- and LRRK2-Induced Neurite Degeneration in Cell Models of Parkinson’s Disease

Parkinson’s disease (PD) is a neurodegenerative disease characterised by the progressive degeneration of midbrain dopaminergic neurons, coupled with the intracellular accumulation of α-synuclein. Axonal degeneration is a central part of the pathology of PD. While the majority of PD cases are sporadi...

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Detalles Bibliográficos
Autores principales: Anantha, Jayanth, Goulding, Susan R., Tuboly, Eszter, O’Mahony, Adam G., Moloney, Gerard M., Lomansey, Gareth, McCarthy, Cathal M., Collins, Louise M., Sullivan, Aideen M., O’Keeffe, Gerard W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8786793/
https://www.ncbi.nlm.nih.gov/pubmed/34623600
http://dx.doi.org/10.1007/s12035-021-02569-6