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The impact of hydration status and fluid distribution on pulmonary function in COPD patients
Chronic Obstructive Pulmonary Disease (COPD) patients have alterations in body composition. Bioelectrical impedance analysis (BIA) evaluates body composition, hydration status, and fluid distribution. Subjects with fluid disturbances have been found to have lower FEV(1), respiratory muscle strength,...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8786821/ https://www.ncbi.nlm.nih.gov/pubmed/35075255 http://dx.doi.org/10.1038/s41598-022-05192-0 |
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author | Orea-Tejeda, Arturo Gómez-Martínez, Manuel González-Islas, Dulce Flores-Cisneros, Laura Keirns-Davis, Candace Sánchez-Santillán, Rocío Pérez-García, Ilse Martínez-Luna, Nathalie Robles-Hernández, Robinson Sánchez-Moreno, Carlos Orozco-Gutíerrez, Juan José |
author_facet | Orea-Tejeda, Arturo Gómez-Martínez, Manuel González-Islas, Dulce Flores-Cisneros, Laura Keirns-Davis, Candace Sánchez-Santillán, Rocío Pérez-García, Ilse Martínez-Luna, Nathalie Robles-Hernández, Robinson Sánchez-Moreno, Carlos Orozco-Gutíerrez, Juan José |
author_sort | Orea-Tejeda, Arturo |
collection | PubMed |
description | Chronic Obstructive Pulmonary Disease (COPD) patients have alterations in body composition. Bioelectrical impedance analysis (BIA) evaluates body composition, hydration status, and fluid distribution. Subjects with fluid disturbances have been found to have lower FEV(1), respiratory muscle strength, and poor prognosis. We aimed to evaluate the effect of hydration status and fluid distribution on pulmonary function in COPD patients. A cross-sectional study, 180 patients with a confirmed diagnosis of COPD were included. Patients with asthma, advanced renal or liver disease, acute HF, exacerbation of COPD, or pacemakers were excluded. Hydration status variables (TBW, ECW, ICW) and disturbance of fluid distribution [impedance ratio (IR) > 0.84 and phase angle (PhA)] were evaluated by BIA. Pulmonary function was assessed by spirometry. The mean population age was 71.55 ± 8.94 years; 55% were men. Subjects were divided into two groups according to the IR ≥ 0.84 or < 0.84. The group with higher IR ≥ 0.84 had lower FEV(1), FVC, FEV(1)/FVC, DLCO and, PhA compared to those with IR < 0.84. After adjusting for confounding variables TBW, ECW, IR ≥ 0.84, PhA, and resistance/height increase were associated with decreased FEV(1). In the same way, with IR ≥ 0.84, edema index ≥ 0.48, trunk and abdominal IR were negatively associated with FVC, and PhA had a positive association with FVC. Fluid distribution, especially IR and PhA, could be a useful parameter for predicting pulmonary function in COPD patients. |
format | Online Article Text |
id | pubmed-8786821 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-87868212022-01-25 The impact of hydration status and fluid distribution on pulmonary function in COPD patients Orea-Tejeda, Arturo Gómez-Martínez, Manuel González-Islas, Dulce Flores-Cisneros, Laura Keirns-Davis, Candace Sánchez-Santillán, Rocío Pérez-García, Ilse Martínez-Luna, Nathalie Robles-Hernández, Robinson Sánchez-Moreno, Carlos Orozco-Gutíerrez, Juan José Sci Rep Article Chronic Obstructive Pulmonary Disease (COPD) patients have alterations in body composition. Bioelectrical impedance analysis (BIA) evaluates body composition, hydration status, and fluid distribution. Subjects with fluid disturbances have been found to have lower FEV(1), respiratory muscle strength, and poor prognosis. We aimed to evaluate the effect of hydration status and fluid distribution on pulmonary function in COPD patients. A cross-sectional study, 180 patients with a confirmed diagnosis of COPD were included. Patients with asthma, advanced renal or liver disease, acute HF, exacerbation of COPD, or pacemakers were excluded. Hydration status variables (TBW, ECW, ICW) and disturbance of fluid distribution [impedance ratio (IR) > 0.84 and phase angle (PhA)] were evaluated by BIA. Pulmonary function was assessed by spirometry. The mean population age was 71.55 ± 8.94 years; 55% were men. Subjects were divided into two groups according to the IR ≥ 0.84 or < 0.84. The group with higher IR ≥ 0.84 had lower FEV(1), FVC, FEV(1)/FVC, DLCO and, PhA compared to those with IR < 0.84. After adjusting for confounding variables TBW, ECW, IR ≥ 0.84, PhA, and resistance/height increase were associated with decreased FEV(1). In the same way, with IR ≥ 0.84, edema index ≥ 0.48, trunk and abdominal IR were negatively associated with FVC, and PhA had a positive association with FVC. Fluid distribution, especially IR and PhA, could be a useful parameter for predicting pulmonary function in COPD patients. Nature Publishing Group UK 2022-01-24 /pmc/articles/PMC8786821/ /pubmed/35075255 http://dx.doi.org/10.1038/s41598-022-05192-0 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Article Orea-Tejeda, Arturo Gómez-Martínez, Manuel González-Islas, Dulce Flores-Cisneros, Laura Keirns-Davis, Candace Sánchez-Santillán, Rocío Pérez-García, Ilse Martínez-Luna, Nathalie Robles-Hernández, Robinson Sánchez-Moreno, Carlos Orozco-Gutíerrez, Juan José The impact of hydration status and fluid distribution on pulmonary function in COPD patients |
title | The impact of hydration status and fluid distribution on pulmonary function in COPD patients |
title_full | The impact of hydration status and fluid distribution on pulmonary function in COPD patients |
title_fullStr | The impact of hydration status and fluid distribution on pulmonary function in COPD patients |
title_full_unstemmed | The impact of hydration status and fluid distribution on pulmonary function in COPD patients |
title_short | The impact of hydration status and fluid distribution on pulmonary function in COPD patients |
title_sort | impact of hydration status and fluid distribution on pulmonary function in copd patients |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8786821/ https://www.ncbi.nlm.nih.gov/pubmed/35075255 http://dx.doi.org/10.1038/s41598-022-05192-0 |
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