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Hyperpolarised (13)C-MRI identifies the emergence of a glycolytic cell population within intermediate-risk human prostate cancer

Hyperpolarised magnetic resonance imaging (HP (13)C-MRI) is an emerging clinical technique to detect [1-(13)C]lactate production in prostate cancer (PCa) following intravenous injection of hyperpolarised [1-(13)C]pyruvate. Here we differentiate clinically significant PCa from indolent disease in a l...

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Detalles Bibliográficos
Autores principales: Sushentsev, Nikita, McLean, Mary A., Warren, Anne Y., Benjamin, Arnold J. V., Brodie, Cara, Frary, Amy, Gill, Andrew B., Jones, Julia, Kaggie, Joshua D., Lamb, Benjamin W., Locke, Matthew J., Miller, Jodi L., Mills, Ian G., Priest, Andrew N., Robb, Fraser J. L., Shah, Nimish, Schulte, Rolf F., Graves, Martin J., Gnanapragasam, Vincent J., Brindle, Kevin M., Barrett, Tristan, Gallagher, Ferdia A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8786834/
https://www.ncbi.nlm.nih.gov/pubmed/35075123
http://dx.doi.org/10.1038/s41467-022-28069-2

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