Silencing acetyl-CoA carboxylase A and sterol regulatory element-binding protein 1 genes through RNAi reduce serum and egg cholesterol in chicken

Cholesterol is synthesized in chicken through de novo lipid biosynthetic pathway where two most important genes viz. SREBP1 and ACACA play immense role. To minimize cholesterol synthesis, RNAi approach was adopted and accordingly, we developed transgenic chicken possessing ACACA and SREBP1 shRNA con...

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Detalles Bibliográficos
Autores principales: Prasad, Athe Rajendra, Bhattacharya, T. K., Chatterjee, R. N., Divya, D., Bhanja, S. K., Shanmugam, M., Sagar, N. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8786841/
https://www.ncbi.nlm.nih.gov/pubmed/35075178
http://dx.doi.org/10.1038/s41598-022-05204-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8786841/
https://www.ncbi.nlm.nih.gov/pubmed/35075178
http://dx.doi.org/10.1038/s41598-022-05204-z

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